Biophotonic materials and uses thereof
The present disclosure provides topical biophotonic materials and methods useful in phototherapy. In particular, the topical biophotonic materials of the present disclosure include a cohesive matrix, and at least one chromophore which can absorb and emit light from within the topical biophotonic material, wherein the topical biophotonic material is elastic. The topical bio-photonic materials and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.
1. A method for promoting would healing, the method comprising:
placing an elastic biophotonic material within a wound, wherein the elastic biophotonic material comprises at least one chromophore present in the elastic biophotonic material in an amount ranging from about 0.001% and about 3% per weight of the elastic biophotonic material and a cohesive matrix comprising silicone and hyaluronate; and
applying light through the elastic biophotonic material, wherein the light has a wavelength that overlaps with an absorption spectrum of the at least one chromophore;
wherein said elastic biophotonic material emits fluorescence that promotes wound healing.
2. A method as defined in claim 1 , wherein the elastic biophotonic material is operatively coupled to a light source.
3. A method as defined in claim 1 , wherein the at least one chromophore is a xanthene dye.
4. A method as defined in claim 3 , wherein the xanthene dye is Eosin Y, Erythrosine B, Fluorescein, Rose Bengal, or Phloxin B.
5. A method as defined in claim 1 , wherein the elastic biophotonic material further comprises an oxygen-rich compound.
6. A method as defined in claim 5 , wherein the oxygen-rich compound is selected from hydrogen peroxide, carbamide peroxide and benzoyl peroxide.
7. A method as defined in claim 1 , wherein the elastic biophotonic material has a thickness of about 1 mm to about 10 mm.
8. A method as defined in claim 1 , wherein the elastic biophotonic material comprises one or more waveguide extending at least partially through the elastic biophotonic material.
9. A method as defined in claim 8 , wherein the one or more waveguide is operatively connected to a light source.