Systems and methods for fluid delivery
The invention provides for a delivery system including a delivery assembly configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery assembly configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery). The delivery assembly is generally configured to be filled on-site and in the field and is further capable of delivery of the agent in a controlled manner and without requiring specialized skill in administering delivery of such agent.
1. A modular injectable delivery system for injection of a fluid agent from a BFS vial into a patient, the modular injectable delivery system comprising:
an administration member for injecting the fluid agent into the patient, the administration member comprising a needle defining a distal end and a proximate end, the distal end comprising a point for piercing the patient, the administration member being retained by a thermoplastic polymer element, and the thermoplastic polymer element comprising a first molded coupling feature adjacent to the proximate end of the needle; and
a fluid delivery hub defining a cylindrical body comprising a first end and a second end, the fluid delivery hub comprising a second molded coupling feature at the second end thereof, defining a bore between the first and second ends, and comprising a recess within the bore proximate to the first end thereof, the bore at the first end being shaped to receive a neck of a BFS vial containing the fluid agent and the recess being shaped to receive a mating feature of the neck of the BFS vial, and the second molded coupling feature being selectively engaged with the first molded coupling feature of the thermoplastic polymer element.
2. The modular injectable delivery system of claim 1 , wherein the mating feature of the neck of the BFS vial comprises a rounded exterior flange.
3. The modular injectable delivery system of claim 1 , further comprising:
a removable cap selectively coupled to cover the distal end of the needle.
4. The modular injectable delivery system of claim 1 , wherein the neck of the BFS vial is cylindrically shaped, in fluid communication with a fluid reservoir containing the fluid agent, and comprises a seal at an end thereof.
5. The modular injectable delivery system of claim 1 , further comprising:
the BFS vial.