IP Library Granted Patent US 10,767,973
Granted Patent B2
US 10,767,973 · App. 16/173,146 · Granted Sep 8, 2020

Dual-edge sampling with k-clock to avoid aliasing in optical coherence tomography

Inventors: Bing Wang (Laguna Niguel, CA); Muhammad K. Al-Qaisi (Ladera Ranch, CA); Hugang Ren (Cypress, CA)
Assignee: Alcon Inc.
G01B9/02084A61B3/102A61B5/0066A61B5/7257G01B9/02004G01B9/02091A61B5/725
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,767,973
App. No.
16/173,146
Granted
Sep 8, 2020
Kind
B2
Abstract

Techniques and apparatus for producing sampled Optical Coherence Tomography (OCT) interference signals without aliasing, based on a swept-source OCT interference signal. An example apparatus comprises a k-clock circuit configured to selectively output a k-clock signal at any of a plurality of k-clock frequencies ranging from a minimum k-clock frequency to a maximum k-clock frequency, and an anti-aliasing filter configured to filter a swept-source OCT interference signal, to produce a filtered OCT interference signal, where the anti-aliasing filter has a cut-off frequency greater than one-half the minimum k-clock frequency but less than the minimum k-clock frequency. The apparatus further comprises an analog-to-digital (A/D) converter circuit configured to sample the filtered OCT interference signal at twice the k-clock frequency, to produce a sampled OCT interference signal. In some embodiments, the A/D converter circuit samples the filtered OCT interference signal at both rising and falling edges of the k-clock signal.

Claims (27)

1. An Optical Coherence Tomography (OCT) data acquisition and processing circuit for use in producing an OCT image based on a swept-source OCT interference signal, the OCT data acquisition and processing circuit comprising:

a k-clock configured to selectively output a k-clock signal at any of a plurality of k-clock frequencies ranging from a minimum k-clock frequency to a maximum k-clock frequency;

an anti-aliasing filter configured to filter the swept-source OCT interference signal, to produce a filtered OCT interference signal, the anti-aliasing filter having a cut-off frequency greater than one-half the minimum k-clock frequency but less than the minimum k-clock frequency; and

an analog-to-digital (A/D) converter circuit coupled to an output of the anti-aliasing filter and configured to sample the filtered OCT interference signal at twice the k-clock frequency, to produce a sampled OCT interference signal;

wherein the A/D converter circuit comprises first and second A/D converters, the first A/D converter being configured to sample the filtered OCT interference signal at the k-clock frequency, using the k-clock signal, and the second A/D converter being configured to separately sample the filtered OCT interference signal at the k-clock frequency, using a phase-shifted replica of the k-clock signal, the A/D converter circuit further comprising a multiplexer to combine the sampled outputs from the first and second A/D converters to obtain the sampled OCT interference signal.

2. An OCT system comprising the OCT data acquisition and processing circuit of claim 1 , and further comprising:

a swept optical source; and

an interferometer coupled to an output of the swept optical source, the interferometer comprising a detector circuit configured to generate the swept-source OCT interference signal from an optical interference signal produced by the interferometer.

3. An OCT system comprising the OCT data acquisition and processing circuit of claim 1 , and further comprising:

a digital signal processing circuit configured to process the sampled OCT interference signal to obtain an OCT image; and

a display configured to display the OCT image.

4. The OCT data acquisition and processing circuit of claim 1 , further comprising:

a k-clock doubler configured to produce the phase-shifted replica of the k-clock signal.

5. An Optical Coherence Tomography (OCT) data acquisition and processing circuit comprising:

a k-clock configured to selectively output a k-clock signal at any of a plurality of k-clock frequencies ranging from a minimum k-clock frequency to a maximum k-clock frequency;

a k-clock doubler configured to produce a phase-shifted replica of the k-clock signal;

an anti-aliasing filter configured to filter the swept-source OCT interference signal, to produce a filtered OCT interference signal, the anti-aliasing filter having a cut-off frequency greater than one-half the minimum k-clock frequency but less than the minimum k-clock frequency;

first and second A/D converters, the first A/D converter being configured to sample the filtered OCT interference signal at the k-clock frequency, using the k-clock signal, and the second A/D converter being configured to separately sample the filtered OCT interference signal at the k-clock frequency, using the phase-shifted replica of the k-clock signal, the A/D converter circuit further comprising a multiplexer to combine the sampled outputs from the first and second A/D converters to obtain the sampled OCT interference signal;

a digital signal processor, an input of the digital signal processor coupled to an output of the analog-to-digital (A/D) converter circuit;

the multiplexer coupled to an output of the first A/D converter and to an output of the second A/D converter; and

the digital signal processor coupled to an output of the multiplexer.

6. An OCT system comprising the OCT data acquisition and processing circuit of claim 5 , and further comprising:

a swept optical source; and

an interferometer coupled to an output of the swept optical source, the interferometer comprising a detector circuit configured to generate the swept-source OCT interference signal from an optical interference signal produced by the interferometer.

7. An OCT system comprising the OCT data acquisition and processing circuit of claim 5 , and further comprising:

a digital signal processing circuit configured to process the sampled OCT interference signal to obtain an OCT image; and

a display configured to display the OCT image.

Assignments (3)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 29, 2018
From: ALCON RESEARCH, LTD.
To: NOVARTIS AG
Reel/Frame 047338/0100 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 29, 2018
From: WANG, BING; AL-QAISI, MUHAMMAD; REN, HUGANG
To: ALCON RESEARCH, LTD.
Reel/Frame 047347/0183 →