IP Library Granted Patent US 10,916,027
Granted Patent B2
US 10,916,027 · App. 16/179,272 · Granted Feb 9, 2021

Determining centerlines in elongated structures in images to detect abnormalities

Inventors: Arkadiusz Sitek (Ashland, MA); Yiting Xie (Cambridge, MA); Ben Graf (Boston, MA)
Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
G06T7/60G06T2207/10072G06T2207/20081G06T2207/30028G06T2207/30101G06T2207/30172
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Quick Facts
Patent No.
US 10,916,027
App. No.
16/179,272
Granted
Feb 9, 2021
Kind
B2
Abstract

Systems and methods for determining an abnormality in an elongated structure in a three dimensional medical image. One system includes an electronic processor. The electronic processor is configured to determine a centerline of the elongated structure in the three dimensional medical image and determine a plurality of two dimensional cross sections of the three dimensional medical image based on the centerline. For each two dimensional cross section of the plurality of two dimensional cross sections, the electronic processor is configured to convert the two dimensional cross section to polar coordinates, fit a line to the elongated structure in the two dimensional cross section converted to polar coordinates, and reconvert the two dimensional cross section to Cartesian coordinates.

Claims (44)

1. A system for determining an abnormality in an elongated structure in a three dimensional medical image, the system comprising

an electronic processor configured to:

determine a centerline of the elongated structure in the three dimensional medical image;

determine a plurality of two dimensional cross sections of the three dimensional medical image based on the centerline; and

for each two dimensional cross section of the plurality of two dimensional cross sections;

convert the two dimensional cross section to polar coordinates;

fit a line to the elongated structure in the two dimensional cross section converted to polar coordinates; and

reconvert the two dimensional cross section to Cartesian coordinates.

2. The system according to claim 1 , wherein the electronic processor is further configured to:

determine a diameter of the elongated structure in the two dimensional cross section; and

when the diameter exceeds a predetermined threshold and the elongated structure is an artery, determine the elongated structure is aneurysmal.

3. The system according to claim 1 , wherein the electronic processor is further configured to

determine a diameter of the elongated structure in the two dimensional cross section by using the line fitted to the elongated structure in the two dimensional cross section converted to polar coordinates.

4. The system according to claim 1 , wherein the line fitted to the elongated structure in the two dimensional cross section indicates a circumference of the elongated structure.

5. The system according to claim 1 , wherein the elongated structure is one selected from the group consisting of an artery, a colon, or an esophagus.

6. The system according to claim 1 , wherein the electronic processor is configured to determine the centerline of the elongated structure in the three dimensional medical image by using artificial intelligence software.

7. The system according to claim 6 , wherein the electronic processor is further configured to train the artificial intelligence software to determine the centerline of the elongated structure in the three dimensional medical image using a training set including a plurality of training examples.

8. The system according to claim 7 , wherein the electronic processor is further configured to create a training example by

receiving a plurality of reference points for a subset of a plurality of slices of a second three dimensional medical image, each of the plurality of reference points marking a centerline of the elongated structure within one of the subset of the plurality of slices of the second three dimensional medical image;

receiving a selection of a starting reference point within the plurality of reference points;

determining an order of the plurality of reference points; and

fitting a spline curve to the plurality of reference points based on the order of the reference points to define a marked centerline of the second three medical dimensional image to create the training example.

9. A method of determining an abnormality in an elongated structure in a three dimensional medical image, the method comprising

determining a centerline of the elongated structure in the three dimensional medical image;

determining a plurality of two dimensional cross sections of the three dimensional medical image based on the centerline; and

for each two dimensional cross section of the plurality of two dimensional cross sections;

converting the two dimensional cross section to polar coordinates;

fitting a line to the elongated structure in the two dimensional cross section converted to polar coordinates; and

reconverting the two dimensional cross section to Cartesian coordinates.

10. The method according to claim 9 , the method further comprising:

determining a diameter of the elongated structure in the two dimensional cross section; and

when the diameter exceeds a predetermined threshold and the elongated structure is an artery, determining the elongated structure is aneurysmal.

11. The method according to claim 9 , the method further comprising

determining a diameter of the elongated structure in the two dimensional cross section by using the line fitted to the elongated structure in the two dimensional cross section converted to polar coordinates.

12. The method according to claim 9 , wherein the line fitted to the elongated structure in the two dimensional cross section indicates a circumference of the elongated structure.

13. The method according to claim 9 , wherein the elongated structure is one selected from a group consisting of an artery, a colon, or an esophagus.

14. The method according to claim 9 , wherein determining the centerline of the elongated structure in the three dimensional medical image includes using artificial intelligence software to determine the centerline.

15. The method according to claim 14 , wherein the method further comprising: training the artificial intelligence software to determine the centerline of the elongated structure in the three dimensional medical image using a training set including a plurality of training examples.

16. The system according to claim 15 , the method further comprising:

creating a training example for the plurality of training examples by:

receiving a plurality of reference points for a subset of a plurality of slices of a second three dimensional medical image, each of the plurality of reference points marking a centerline of the elongated structure within one of the subset of the plurality of slices of the second three dimensional medical image;

receiving a selection of a starting reference point within the plurality of reference points;

determining an order of the plurality of reference points; and

fitting a spline curve to the plurality of reference points based on the order of the reference points to define a marked centerline of the second three dimensional medical image to create the training example.

Assignments (4)
SECURITY INTEREST Recorded Oct 1, 2025
From: MERATIVE US L.P.; MERGE HEALTHCARE INCORPORATED
To: TCG SENIOR FUNDING L.L.C., AS COLLATERAL AGENT
Reel/Frame 072808/0442 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 21, 2022
From: INTERNATIONAL BUSINESS MACHINES CORPORATION
To: MERATIVE US L.P.
Reel/Frame 061496/0752 →
CORRECTIVE ASSIGNMENT TO CORRECT THE SPELLING OF BEN GRAF NAME PREVIOUSLY RECORDED ON REEL 047413 FRAME 0567. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Mar 29, 2021
From: SITEK, ARKADIUSZ; XIE, YITING; GRAF, BENEDIKT
To: INTERNATIONAL BUSINESS MACHINES CORPORATION
Reel/Frame 055761/0544 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 5, 2018
From: SITEK, ARKADIUSZ; XIE, YITING; GRAF, BEN
To: INTERNATIONAL BUSINESS MACHINES CORPORATION
Reel/Frame 047413/0567 →
Continuity (2)
Continuation 16179138 · Nov 2, 2018
Related Publication 20200143556A1 · May 7, 2020