Method of assembly of a modular sterile facility
A modular vivarium is assembled from pre-manufactured, transportable, sterile modules of distinct types, called pods. A hallway pod forms a spine, with cage-rack pods, ingress/egress pods and optional HVACPIT pods providing HVAC, power and IT services connected as spur pods to the hallway. Supplies and waste are also within modular pods. Temporary or single-use seals cover doorways during transit. Modules are joined or removed while maintaining sterility on both sides of the flush-to-wall doorway junction. A spur pod is sterilely connected to a hallway pod by aligning respective doors proximal, placing a seal between the pods around the doorways, sterilizing air between the pods, then removing the temporary seals from each doorway. Pods may be constructed from easily transportable ISO intermodal containers.
1. A method of assembling a modular vivarium comprising the steps:
placing a rectangular, pre-manufactured sterile hallway pod comprising a plurality of sealed side doorways on its sides and at least one sealed end doorway on one end;
placing a plurality of rectangular, pre-manufactured sterile cage-rack pods, each comprising a sealed doorway on one end, proximal to and perpendicular to the hallway pod such that the doorway of the each cage-rack pods is aligned with an associated side doorway of the hallway pod;
unsealing the sealed doorways at the ends of the cage-rack pods and unsealing the associated side doorway of the hallway pod such that the sterility of the hallway pod and the sterility of the cage-rack pods are preserved and interior air of the each cage-rack pod and interior air of the hallway pod are now in common.
2. The method of assembling a modular vivarium of claim 1 wherein:
the hallway pod comprises at least six side doorways.
3. The method of assembling a modular vivarium of claim 1 wherein:
the hallway pod comprises eight side doorways.
4. The method of assembling a modular vivarium of claim 1 wherein:
the modular vivarium comprises at least four cage-rack pods.
5. The method of assembling a modular vivarium of claim 1 wherein:
the modular vivarium comprises eight cage-rack pods.
6. The method of assembling a modular vivarium of claim 1 wherein:
the modular vivarium comprises at least two HVACPIT pods and wherein the at least two HVACPIT pods operate redundantly such that if a first HVACPIT pod fails that a second HVACPIT provides sufficient ventilation for the modular vivarium for the vivarium to continue normal operation.
7. The method of assembling a modular vivarium of claim 1 comprising the additional step:
placing a rectangular, pre-manufactured ingress pod comprising at least one sealed external doorway and comprising one sealed mating doorway proximal to the hallway pod such that the mating doorway of the ingress pod aligns with a doorway of the hallway pod; wherein the ingress pod comprises a region for gowning and cleaning of personnel entering the modular vivarium.