IP Library Granted Patent US 10,916,015
Granted Patent B2
US 10,916,015 · App. 16/199,423 · Granted Feb 9, 2021

Segmentation in optical coherence tomography imaging

Inventor: Hugang Ren (Cypress, CA)
Assignee: Alcon Inc.
G06T7/174A61B3/102G06T5/50G06T7/11G06T7/12G06T2207/10056G06T2207/10101G06T2207/20192G06T2207/20224G06T2207/30041
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Quick Facts
Patent No.
US 10,916,015
App. No.
16/199,423
Granted
Feb 9, 2021
Kind
B2
Abstract

A method for improving segmentation in optical coherence tomography imaging. The method comprises obtaining an OCT image of imaged tissue, generating a first feature image for at least a portion of the OCT image, and generating a second feature image for at least the portion of the OCT image, based on either the OCT image or the first feature image, by integrating image data in a first direction across the OCT image or first feature image. A third feature image is generated as a mathematical function of the first and second feature images, and layer segmentation for the OCT image is performed, based on the third feature image.

Claims (19)

1. A method for improving segmentation in optical coherence tomography (OCT) imaging, the method comprising:

obtaining an OCT image of imaged tissue, wherein the OCT image comprises a plurality of A-lines;

generating a first feature image for at least a portion of the OCT image;

generating a second feature image for at least the portion of the OCT image, based on either the OCT image or the first feature image, by integrating image data in a first direction across the OCT image or first feature image, wherein generating the second feature image comprises, for each of the A-lines, integrating image data from the OCT image or the first feature image in a direction along the A-line, from a bottom edge of the OCT image or the first feature image towards the opposite edge;

generating a third feature image as a mathematical function of the first and second feature images; and

performing layer segmentation for the OCT image, based on the third feature image.

2. The method of claim 1 , wherein generating the first feature image for at least the portion of the OCT image comprises calculating gradients along a row direction of the OCT image, or a column direction of the OCT image, or both, to obtain the first feature image.

3. The method of claim 1 , wherein generating the third feature image comprises subtracting the second feature image from the first feature image.

4. The method of claim 1 , further comprising displaying a visual representation of the OCT image, the visual representation including an indication of the layer segmentation.

5. An Optical Coherence Tomography (OCT) imaging apparatus, comprising:

a communication interface configured to obtain an OCT image of imaged tissue, wherein the OCT image comprises a plurality of A-lines; and

a processing circuit operatively coupled to the communication interface and configured to:

generate a first feature image for at least a portion of the OCT image;

generate a second feature image for at least the portion of the OCT image, based on either the OCT image or the first feature image, by integrating image data in a first direction across the OCT image or first feature image, wherein the processing circuit is configured to generate the second feature image by, for each of the A-lines, by integrating image data from the OCT image or the first feature image in a direction along the A-line, from a bottom edge of the OCT image or the first feature image towards the opposite edge;

generate a third feature image as a mathematical function of the first and second feature images; and

perform layer segmentation for the OCT image, based on the third feature image.

6. The OCT imaging apparatus of claim 5 , wherein the processing circuit is configured to generate the first feature image for at least the portion of the OCT image by calculating gradients along a row direction of the OCT image, or a column direction of the OCT image, or both, to obtain the first feature image.

7. The OCT imaging apparatus of claim 5 , wherein the processing circuit is configured to generate the third feature image by subtracting the second feature image from the first feature image.

8. The OCT imaging apparatus of claim 5 , further comprising a display, wherein the processing circuit is configured to use or cause the display to display a visual representation of the OCT image, the visual representation including an indication of the layer segmentation.

Assignments (3)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 26, 2018
From: REN, HUGANG
To: ALCON RESEARCH, LTD.
Reel/Frame 047579/0042 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 26, 2018
From: ALCON RESEARCH, LTD.
To: NOVARTIS AG
Reel/Frame 047579/0077 →