IP Library Granted Patent US 11,253,849
Granted Patent B2
US 11,253,849 · App. 16/203,119 · Granted Feb 22, 2022

Systems and methods for onsite sorbent material reuse

Inventors: Yuanpang Samuel Ding (Long Grove, IL); Rosa Hung-Chen Yeh (Libertyville, IL); Cristian Adolfo Menzel Bueno (Gurnee, IL); Ieng Kin Lao (Taipa, MO)
Assignees: Baxter International Inc.; Baxter Healthcare SA
B01J49/53A61L2/18A61L2/26A61M1/169B01D15/203B01D15/362B01J39/02B01J39/12B01J47/016B01J47/024B01J49/06B01J49/60A61L2202/17A61L2202/24
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Quick Facts
Patent No.
US 11,253,849
App. No.
16/203,119
Granted
Feb 22, 2022
Kind
B2
Abstract

Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H + ZP within a casing for a treatment; and after the treatment, refurbishing the H + ZP while maintained within the casing via (i) regenerating the non-disinfected H + ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H + ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H + ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H + ZP while maintained within the casing. Multiple batch sorbent refurbishing implementations are also disclosed.

Claims (40)

1. A medical fluid delivery method comprising:

providing a sorbent cartridge including H + ZP within a casing for a treatment; and

after the treatment, refurbishing the H + ZP while maintained within the casing via

regenerating the non-disinfected H + ZP by flowing an acid solution through the casing,

rinsing the regenerated H + ZP while maintained within the casing,

disinfecting the regenerated and rinsed H + ZP by flowing a disinfecting agent through the casing, and

rinsing the regenerated and disinfected H + ZP while maintained within the casing,

wherein the casing including the refurbished H + ZP is replaced within the sorbent cartridge along with at least one new and different type of casing.

2. The medical fluid delivery method of claim 1 , wherein at least one of the rinsing procedures includes rinsing the H + ZP with water through the casing until a desired conductivity is reached.

3. The medical fluid delivery method of claim 1 , wherein the first rinsing procedure includes rinsing the H + ZP with water through the casing in a reverse-to-treatment flow direction and the second rinsing procedure includes rinsing the H + ZP with water through the casing in a normal treatment flow direction.

4. The medical fluid delivery method of claim 1 , wherein disinfecting the rinsed and regenerated H + ZP includes flowing the disinfecting agent through the casing in a reverse-to-treatment flow direction.

5. The medical fluid delivery method of claim 1 , wherein regenerating the non-disinfected H + ZP includes flowing the acid solution through the casing in a reverse-to-treatment flow direction.

6. The medical fluid delivery method of claim 1 , wherein regenerating the non-disinfected H + ZP includes at least one of flowing the acid solution through the casing (i) at a flowrate of 0.1 ml/min to 5 ml/min, (ii) at a temperature from about 20° C. to about 80° C., or (iii) until eluent acid used to contact the H + ZP has a pH that equals or substantially equals a pH of incoming acid solution.

7. The medical fluid delivery method of claim 1 , wherein at least one of (a) the acid solution is HCl, H 2 SO 4 , H 3 PO 4 , HNO 3 or acetic acid or (b) the disinfecting agent (i) is a hydrogen based chemical, such as including HOCl or (ii) includes isopropyl alcohol (“IPA”).

8. A medical fluid delivery method comprising:

providing a sorbent cartridge including Na + ZP within a casing for a treatment; and

after the treatment,

refurbishing the Na + ZP while maintained within the casing via regenerating the non-disinfected Na + ZP using by flowing a sodium based alkaline solution or a sodium salt solution through the casing,

rinsing the regenerated Na + ZP while maintained within the casing,

disinfecting the regenerated and rinsed Na + ZP by flowing a disinfecting agent through the casing, and

rinsing the regenerated and disinfected Na + ZP while maintained within the casing,

wherein the casing including the refurbished Na + ZP is replaced within the sorbent cartridge along with at least one new and different type of casing.

9. The medical fluid delivery method of claim 8 , wherein at least one of the rinsing procedures includes rinsing the Na + ZP with water through the casing until a desired conductivity is reached.

10. The medical fluid delivery method of claim 8 , wherein the first rinsing procedure includes rinsing the Na + ZP with water through the casing in a reverse-to-treatment flow direction and the second rinsing procedure includes rinsing the Na + ZP with water through the casing in a normal treatment flow direction.

11. The medical fluid delivery method of claim 8 , wherein disinfecting the rinsed and regenerated Na + ZP includes flowing the disinfecting agent through the casing in a reverse-to-treatment flow direction.

12. The medical fluid delivery method of claim 8 , wherein regenerating the non-disinfected Na + ZP includes flowing the sodium based alkaline solution or the sodium salt solution through the casing in a reverse-to-treatment flow direction.

13. The medical fluid delivery method of claim 8 , wherein regenerating the non-disinfected Na + ZP includes at least one of flowing the sodium based alkaline solution or the sodium salt solution through the casing (i) at a flowrate of 0.1 ml/min to 5 ml/min, (ii) at a temperature from about 20° C. to about 80° C., or (iii) until eluent sodium solution used to contact the Na + ZP has a conductivity that equals or substantially equals a conductivity of incoming sodium solution.

14. The medical fluid delivery method of claim 8 , wherein the disinfecting agent (i) is a sodium based chemical, such as including NaOCl or (ii) includes isopropyl alcohol (“IPA”).

15. A medical fluid delivery method comprising:

providing a sorbent cartridge including Na + ZP within a casing for a treatment; and

after the treatment, refurbishing the Na + ZP while maintained within the casing via

disinfecting the non-regenerated Na + ZP by flowing a disinfecting agent through the casing,

rinsing the disinfected Na + ZP while maintained within the casing,

regenerating the disinfected and rinsed Na + ZP by flowing a sodium based alkaline solution or a sodium salt solution through the casing, and

rinsing the disinfected and regenerated Na + ZP while maintained within the casing,

wherein the casing including the refurbished Na + ZP is replaced within the sorbent cartridge along with at least one new and different type of casing.

16. The medical fluid delivery method of claim 15 , wherein at least one of the rinsing procedures includes rinsing the Na + ZP with water through the casing until a desired conductivity is reached.

17. The medical fluid delivery method of claim 15 , wherein the second rinsing procedure includes rinsing the Na + ZP with water through the casing in a normal treatment flow direction.

18. The medical fluid delivery method of claim 15 , wherein regenerating the disinfected Na + ZP includes at least one of flowing the sodium based alkaline solution or the sodium salt solution through the casing (i) at a flowrate of 0.1 ml/min to 5 ml/min, (ii) at a temperature from about 20° C. to about 80° C., or (iii) until eluent sodium solution used to contact the Na + ZP has a conductivity that equals or substantially equals a conductivity of incoming sodium solution.

19. The medical fluid delivery method of claim 15 , wherein the disinfecting agent (i) is a sodium based chemical, such as including NaOCl or (ii) includes isopropyl alcohol (“IPA”).

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER INTERNATIONAL INC.
To: VANTIVE US HEALTHCARE LLC
Reel/Frame 074042/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER HEALTHCARE SA
To: VANTIVE HEALTH GMBH
Reel/Frame 074046/0139 →
SECURITY INTEREST Recorded Jan 31, 2025
From: VANTIVE US HEALTHCARE LLC; GAMBRO RENAL PRODUCTS, INC.
To: ARES CAPITAL CORPORATION
Reel/Frame 070076/0701 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 8, 2019
From: DING, YUANPANG SAMUEL; YEH, ROSA HUNG-CHEN; MENZEL BUENO, CRISTIAN ADOLFO
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
Reel/Frame 050004/0380 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 8, 2019
From: LAO, LENG KIN
To: BAXTER HEALTHCARE (SUZHOU) CO., LTD.
Reel/Frame 050004/0950 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 8, 2019
From: BAXTER HEALTHCARE (SUZHOU) CO., LTD.
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
Reel/Frame 050013/0001 →
Continuity (1)
Related Publication 20200164357A1 · May 28, 2020