IP Library Granted Patent US 11,653,830
Granted Patent B2
US 11,653,830 · App. 16/213,602 · Granted May 23, 2023

Multi-view ophthalmic diagnostic systems

Inventors: Martin Gründig (Rangsdorf, DE); Peter Zieger (Teltow, DE)
Assignee: Alcon Inc.
A61B3/102A61B3/0008A61B3/103A61B3/107
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Quick Facts
Patent No.
US 11,653,830
App. No.
16/213,602
Granted
May 23, 2023
Kind
B2
Abstract

A multi-view diagnostic system includes an OCT engine and a plurality of optical elements defining a plurality of beam paths between the OCT engine and an ophthalmic target, with each beam path corresponding to a different viewing angle of the ophthalmic target. The system also includes a scanner to direct OCT imaging beams generated by the OCT engine toward the ophthalmic target along each respective beam path. Instructions stored in memory are executable by a processor to determine a characteristic of the ophthalmic target based on OCT light reflected by the ophthalmic target along each respective beam path and detected by the OCT engine.

Claims (31)

1. A multi-view diagnostic system, comprising:

an OCT engine;

a plurality of optical elements defining a plurality of beam paths between the OCT engine and an ophthalmic target, each beam path corresponding to a different viewing angle of the ophthalmic target;

a scanner configured to direct OCT imaging beams generated by the OCT engine toward the ophthalmic target along each respective beam path, direct first OCT imaging beams toward the ophthalmic target along a first beam path, wherein the first beam path corresponds to one of an optical axis and a visual axis of the ophthalmic target, and direct second OCT imaging beams toward the ophthalmic target along a second beam path defined by a set of static mirrors, wherein the second beam path intersects the first beam path within the ophthalmic target at an acute angle;

an illumination source configured to emit the illumination light, the illumination source comprising a plurality of illumination point sources arranged in one or more concentric patterns around an aperture that allows the OCT imaging beams or other light to pass through to or from the OCT engine;

a beam splitter optically aligned with the OCT engine and a camera optically aligned with the beam splitter, the camera configured to receive illumination light reflected by the ophthalmic target along each respective beam path; and

a processor and instructions stored in a memory, the instructions executable by the processor to:

determine a characteristic of the ophthalmic target based on OCT light reflected by the ophthalmic target along each respective beam path and detected by the OCT engine;

determine an optical intraocular lens (IOL) profile based on the ray tracing analysis and the detected OCT light, wherein the IOL profile includes a power, a shape, or a position of the IOL within the ophthalmic target; and

determine a characteristic of a cornea of the ophthalmic target based on the illumination light reflected by the ophthalmic target along each respective beam path.

2. The system of claim 1 , wherein the instructions are further executable to determine a refractive index of at least one of a cornea, aqueous humor, a lens, or vitreous humor of the ophthalmic target based on the detected OCT light reflected by the ophthalmic target along each respective beam path.

3. The system of claim 1 , wherein the instructions are further executable to generate a three-dimensional model of the ophthalmic target based on the detected OCT light.

4. The system of claim 1 , wherein the plurality of beam paths comprises at least two beam paths which converge and intersect within the ophthalmic target.

5. The system of claim 1 , wherein the instructions are further executable to perform a ray tracing analysis, the ray tracing analysis including a first or second order Purkinje ray tracing analysis.

6. The system of claim 1 , wherein the scanner comprises one or more manipulatable mirrors that selectively direct the OCT imaging beams along one of the beam paths.

7. The system of claim 1 , wherein the determined characteristic of the cornea includes an anterior corneal curvature or a posterior corneal curvature.

8. A method, comprising:

directing multiple OCT imaging beams, from an OCT engine, toward an ophthalmic target along respective beam paths, each beam path defined by a plurality of optical elements and corresponding to a different viewing angle of the ophthalmic target, wherein directing the OCT imaging beams along multiple beam paths comprises:

directing first OCT imaging beams toward the ophthalmic target along a first beam path, wherein the first beam path corresponds to one of an optical axis and a visual axis of the ophthalmic target; and

directing second OCT imaging beams toward the ophthalmic target along a second beam path defined by a set of static mirrors, wherein the second beam path intersects the first beam path within the ophthalmic target at an acute angle,

receiving, along each of the beam paths, reflected OCT light from the ophthalmic target;

emitting, by a plurality of illumination point sources, illumination light toward an ophthalmic target, the illumination source comprising a plurality of illumination point sources arranged in one or more concentric patterns around an aperture that allows the OCT imaging beams or other light to pass through to or from the OCT engine;

receiving illumination light reflected from the ophthalmic target along each of the beam paths;

performing a ray tracing analysis based on the reflected illumination light; and

receiving, via a beam splitter optically aligned with the OCT engine and a camera optically aligned with the beam splitter, illumination light reflected by the ophthalmic target along each respective beam path;

determining one or more characteristics of the ophthalmic target based on the detected OCT light reflected by the ophthalmic target along each respective beam path; and

determining an optical intraocular lens (IOL) profile based on the ray tracing analysis and the detected OCT light, wherein the IOL profile includes a power, a shape, or a position of the IOL within the ophthalmic target; and

determining a characteristic of a cornea of the ophthalmic target based on the illumination light reflected by the ophthalmic target along each respective beam path and based on the ray tracing analysis.

9. The method of claim 8 , wherein the determined characteristic of the ophthalmic target includes an anterior corneal curvature or a posterior corneal curvature.

10. The method of claim 8 , wherein performing the ray tracing analysis comprises performing a first or second order Purkinje ray tracing analysis.

11. The method of claim 8 , comprising generating a three-dimensional eye model of the ophthalmic target based on the detected OCT light reflected by the ophthalmic target along each respective beam path.

Assignments (3)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 10, 2019
From: NOVARTIS AG
To: ALCON INC.
Reel/Frame 051454/0788 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2019
From: GRUNDIG, MARTIN; ZIEGER, PETER
To: WAVELIGHT GMBH
Reel/Frame 047926/0519 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2019
From: WAVELIGHT GMBH
To: NOVARTIS AG
Reel/Frame 047926/0589 →
Continuity (2)
Provisional Application 62608917 · Dec 21, 2017
Related Publication 20190191990A1 · Jun 27, 2019