Reagent reservoir for fluids
A reagent reservoir for fluids, including a storage chamber connected to a duct for conducting fluid out of, into and/or through the storage chamber. The duct includes a duct section delimited by a substrate and a film joined to the substrate. The duct is sealed and is openable at a predetermined breaking point by deflecting the film. The film also delimits the storage chamber and covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall, which is formed in the edge portion and runs parallel to the film, determine the surface area of the joining region.
1. A reagent reservoir for fluids as part of a microfluidic flow cell or as a separate module, comprising:
a substrate;
a storage chamber formed in the substrate;
a channel formed in the substrate and connected to the storage chamber, the channel being closed by a barrier;
a film that delimits the storage chamber and the channel on one side, wherein a contact point between the barrier and the film forms a predetermined breaking point; and
a carrier element that has a dry agent or sample to be analyzed arranged thereon, wherein the carrier element is mounted as a separate part to the reservoir at an opening of the substrate by a conical interference fit or by welding, and wherein the carrier element with the dry reagent or sample boarders the channel downstream of the predetermined breaking point.
2. The reagent reservoir according to claim 1 , wherein the storage chamber is further formed by a bulge in the film.
3. The reagent reservoir according to claim 1 , wherein the predetermined breaking point is breakable by deformation of a portion of the film delimiting the storage chamber, wherein the film delimits the storage chamber and the channel continuously as far as a mouth where the channel opens into a discharging and/or mixing chamber.
4. The reagent reservoir according to claim 1 , wherein the film is a laminate composed of a metal layer and at least one plastic layer, wherein the plastic layer is directed toward the fluid.
5. The reagent reservoir according to claim 4 , wherein the metal layer is an aluminum layer.
6. The reagent reservoir according to claim 5 , wherein the aluminum layer is a soft-annealed aluminum layer.
7. The reagent reservoir according to claim 1 , wherein the substrate has a surface area provided for welding to the film, the surface area having a furrowed structure.
8. The reagent reservoir according to claim 1 , wherein the storage chamber, on a side directed away from the film, has opening channels with in each case an attachment stub that is closeable by welding, wherein the attachment stub is arranged in a depression in the substrate and, in a closed state, is set back in relation to a surface of the substrate directed away from the film.
9. The reagent reservoir according to claim 3 , wherein the discharging and/or mixing chamber forms a socket for connecting the reagent reservoir to an appliance.
10. The reagent reservoir according to claim 3 , wherein the substrate is connected to an actuator and/or a lid.
11. The reagent reservoir according to claim 10 , wherein the actuator and/or the lid is connected to the substrate non-releasably and pivotably.
12. The reagent reservoir according to claim 11 , wherein the actuator and/or the lid is connected to the substrate by a film hinge.
13. The reagent reservoir according to claim 10 , wherein the actuator comprises a stamp element guided through an opening in the lid and deforms the portion of the film, and the stamp element, in an end position of the actuator annuls a height of the storage chamber by the deformation.
14. The reagent reservoir according to claim 10 , wherein the lid and/or the actuator, in an end position, are fixable on the substrate and, optionally, the actuator is fixable on the lid.
15. The reagent reservoir according to claim 14 , wherein the actuator is clamped and/or latched onto the substrate or lid.
16. The reagent reservoir according to claim 10 , wherein the lid together with the substrate forms the discharging and/or mixing chamber.
17. The reagent reservoir according to claim 3 , wherein dry reagent is arranged in the channel or the discharging chamber by the carrier element.