Selectable eccentric remodeling and/or ablation
A catheter and catheter system for treatment of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure. A plurality of electrodes or other electrosurgical energy delivery surfaces can radially engage material to be treated when the structure expands. A material detector near the distal end of the catheter body may measure circumferential material distribution, and a power source selectively energizes the electrodes to eccentrically treat of a body lumen.
1. An apparatus, comprising:
a catheter having a longitudinal axis and configured for placement within a body lumen of a human patient;
an expandable member at a distal portion of the catheter configured to vary between a delivery configuration and a deployed configuration sized to fit within the body lumen of the human patient; and
at least a first pair of bipolar contacts and a second pair of bipolar contacts disposed on the expandable member,
wherein the first pair of bipolar contacts and the second pair of bipolar contacts are spaced apart lengthwise and angularly offset from one another relative to the longitudinal axis when the expandable member is in the deployed configuration,
wherein each of the first pair of bipolar contacts and the second pair of bipolar contacts is configured to deliver thermal energy to less than a full circumference of the body lumen of the human patient,
wherein the body lumen of the human patient is a blood vessel.
2. The apparatus of claim 1 :
wherein the first pair and the second pair of bipolar contacts are configured to deliver thermal energy to create respective first and second non-continuous, circumferential treatment zones along a lengthwise segment of the body lumen of the human patient; and
wherein the first and the second non-continuous, circumferential treatment zones are formed in separate normal radial planes and are not continuous completely around the circumference of the body lumen of the human patient.
3. The apparatus of claim 2 , wherein the first pair and the second pair of bipolar contacts are configured to respectively create the first and the second non-continuous, circumferential treatment zones in sequence.
4. The apparatus of claim 2 , wherein the first pair and the second pair of bipolar contacts are configured to respectively create the first and the second non-continuous, circumferential treatment zones concurrently.
5. The apparatus of claim 1 , further comprising:
a third pair of bipolar contacts disposed on the expandable member; and
a fourth pair of bipolar contacts disposed on the expandable member,
wherein the third pair and fourth pairs of bipolar contacts are angularly offset from one another and from the first and the second pairs of bipolar contacts when the expandable member is in the deployed configuration,
wherein each of the first, the second, the third and the fourth pairs of bipolar contacts are configured to deliver thermal energy to less than a full circumference of the body lumen of the human patient.
6. The apparatus of claim 1 wherein one or both of the first pair and the second pair of bipolar contacts further comprises at least one sensor configured to monitor a parameter of the apparatus or of a tissue of the body lumen of the human patient within the body lumen of the human patient.
7. The apparatus of claim 6 , further comprising a feedback control system configured to alter treatment in response to the monitored parameter.
8. An apparatus, comprising:
a catheter having a longitudinal axis and configured for placement within a body lumen of a human patient;
an expandable member at a distal portion of the catheter, wherein the expandable member has a delivery configuration and a deployed configuration; and
at least a first pair of bipolar contacts and a second pair of bipolar contacts attached to the expandable member and separated lengthwise and radially offset from one another about the longitudinal axis when the expandable member is in the deployed configuration,
wherein each of the first pair of bipolar contacts and the second pair of bipolar contacts is configured to deliver thermal energy to less than a full circumference of the body lumen of the human patient,
wherein the body lumen of the human patient is a blood vessel, and
wherein the expandable member is configured to not block fluid flow within the body lumen of the human patient during energy delivery.
9. The apparatus of claim 8 , wherein the first pair of bipolar contacts further comprises at least one sensor configured to monitor a parameter of the apparatus or of a tissue of the body lumen of the human patient within the human patient.
10. The apparatus of claim 9 , further comprising a feedback control system configured to alter the delivery of thermal energy in response to the monitored parameter.
11. The apparatus of claim 8 , wherein the catheter is configured for infusion of one or more agents into the body lumen of the human patient before, during, or after energy delivery.
12. A method of treatment a human patient using the apparatus of claim 1 , comprising:
inserting the catheter within the body lumen of the human patient;
expanding the expandable member into contact with the body lumen of the human patient in the deployed configuration; and
delivering thermal energy from each of the first pair and the second pair of bipolar contacts to less than a full circumference of the body lumen of the human patient.
13. The method of claim 12 , further comprising:
delivering thermal energy from each of the first pair and the second pair of bipolar contacts to create respective first and second non-continuous, circumferential treatment zones along a lengthwise segment of the body lumen of the human patient; and
forming the first and the second non-continuous, circumferential treatment zones in separate normal radial planes that are not continuous completely around the circumference of the body lumen of the human patient.
14. The method of claim 13 , further comprising creating the first and the second non-continuous, circumferential treatment zones in sequence.
15. The method of claim 13 , further comprising creating the first and the second non-continuous, circumferential treatment zones concurrently.
16. The method of claim 12 , wherein one or both of the first pair and the second pair of bipolar contacts further comprises at least one sensor, and further comprising monitoring a parameter of the catheter or of a tissue within the body lumen of the human patient with the at least one sensor.
17. The method of claim 16 , further comprising altering the delivery of thermal energy in response to the monitored parameter.
18. The method of claim 12 , wherein the thermal energy delivered is sufficient to alter neural activity in neural fibers within a wall of, or in proximity to, the body lumen of the human patient.