IP Library Granted Patent US 10,779,887
Granted Patent B2
US 10,779,887 · App. 16/237,494 · Granted Sep 22, 2020

Systems and methods for creating an effect using microwave energy to specified tissue

Inventors: Mark E. Deem (Mountain View, CA); Daniel E. Francis (Mountain View, CA); Jessi Ernest Johnson (Sunnyvale, CA); Ted Y. Su (Sunnyvale, CA); Steven W. Kim (Los Altos, CA); Alexey Salamini (San Francisco, CA); Peter Smith (Kirkcaldy Fife, GB); Daniel Hallock (Redwood City, CA)
Assignee: MIRADRY, INC.
A61B18/1815A61B18/18A61N5/02A61N5/04A61B90/37A61B2018/00005A61B2018/00023A61B2018/00029A61B2018/00041A61B2018/0047A61B2018/0091A61B2018/00291A61B2018/00779A61B2018/1823A61F2007/0075A61N2005/007
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Quick Facts
Patent No.
US 10,779,887
App. No.
16/237,494
Granted
Sep 22, 2020
Kind
B2
Abstract

Systems, methods and devices for creating an effect using microwave energy to specified tissue are disclosed herein. A system for the application of microwave energy to a tissue can include, in some embodiments, a signal generator adapted to generate a microwave signal having predetermined characteristics, an applicator connected to the generator and adapted to apply microwave energy to tissue, the applicator comprising one or more microwave antennas and a tissue interface, a vacuum source connected to the tissue interface, a cooling source connected to said tissue interface, and a controller adapted to control the signal generator, the vacuum source, and the coolant source. The tissue may include a first layer and a second layer, the second layer below the first layer, and the controller is configured such that the system delivers energy such that a peak power loss density profile is created in the second layer.

Claims (11)

1. A method of raising a temperature of at least a portion of a tissue structure located below an interface between a dermal layer and a subdermal layer of skin, wherein the dermal layer has an upper portion adjacent an external surface of the skin and a lower portion adjacent a subdermal region of the skin, the method comprising the steps of:

positioning a device adapted to radiate microwave energy adjacent the external surface of the skin;

radiating the microwave energy having an electric field component which is substantially parallel to a region of the external surface of the skin above the dermal layer, wherein the microwave energy has a frequency which generates a standing wave pattern in the dermal layer, the standing wave pattern having a constructive interference peak in the lower portion of the dermal layer;

creating a lesion in the lower portion of the dermal layer by heating tissue in the lower portion of the dermal layer using the microwave energy;

removing heat from the skin and at least a portion of the upper portion of the dermal layer to prevent the lesion from spreading into the upper portion of the dermal layer; and

ceasing radiating the microwave energy after a first predetermined time, the first predetermined time being sufficient to raise the temperature of the tissue structure.

2. The method of claim 1 , wherein the first predetermined time comprises a time sufficient to deposit enough of the microwave energy in said lower portion of the dermal layer to enable said lesion to spread into the subdermal region of the skin.

3. The method of claim 1 , wherein the first predetermined time comprises a time sufficient to enable the heat generated by said microwave energy to spread to the tissue structure.

4. The method of claim 1 , wherein the step of removing the heat further comprises continuing to remove the heat for a predetermined time after the step of ceasing radiating the microwave energy.

5. The method of claim 1 , wherein the constructive interference peak is located on a dermal side of the interface between the dermal layer and the subdermal layer of the skin.

6. The method of claim 1 , wherein the lesion starts at the constructive interference peak.

Assignments (13)
SECURITY INTEREST Recorded Oct 1, 2024
From: MIRADRY, INC.
To: WESTERN ALLIANCE BANK
Reel/Frame 068752/0533 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FINANCIAL TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0573 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FUNDING IV TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0486 →
RELEASE OF SECURITY INTEREST (TERM) Recorded Jun 22, 2021
From: MIDCAP FINANCIAL TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0044 →
RELEASE OF SECURITY INTEREST (REVOLVING) Recorded Jun 22, 2021
From: MIDCAP FUNDING IV TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0001 →
REAFFIRMATION AGREEMENT AND AMENDMENT TO SECURITY AGREEMENT (TERM) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 055436/0001 →
SECURITY INTEREST SUPPLEMENT (REVOLVING) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FUNDING IV TRUST, AS AGENT
Reel/Frame 055379/0016 →
CHANGE OF NAME Recorded Jul 18, 2019
From: MIRAMAR TECHNOLOGIES, INC.
To: MIRADRY, INC.
Reel/Frame 049795/0055 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 18, 2019
From: THE FOUNDRY, INC.
To: MIRAMAR LABS, INC.
Reel/Frame 049794/0879 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 18, 2019
From: DEEM, MARK E.; FRANCIS, DAN; JOHNSON, JESSI ERNEST; KIM, STEVEN; SALAMINI, ALEXEY; SU, TED; SMITH, PETER; HALLOCK, DAN
To: THE FOUNDRY, INC.; MIRAMAR LABS, INC.
Reel/Frame 049794/0779 →
CHANGE OF NAME Recorded Jul 18, 2019
From: MIRAMAR LABS, INC.
To: MIRAMAR TECHNOLOGIES, INC.
Reel/Frame 049794/0962 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049650/0001 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049649/0450 →
Continuity (10)
Continuation 15252109 · Aug 30, 2016
Continuation 12107025 · Apr 21, 2008
Continuation In Part PCTUS2008060935 · Apr 18, 2008
Continuation In Part PCTUS2008060929 · Apr 18, 2008
Continuation In Part PCTUS2008060940 · Apr 18, 2008
Continuation In Part PCTUS2008060922 · Apr 18, 2008
Provisional Application 60912899 · Apr 19, 2007
Provisional Application 61013274 · Dec 12, 2007
Provisional Application 61045937 · Apr 17, 2008
Related Publication 20190133684A1 · May 9, 2019
Cited By (2)
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