Heart valve prosthesis
The present disclosure relates to heart valve prostheses, delivery devices, actuation handles, and other improved devices and methods that facilitate delivery of a heart valve prosthesis to a defective native valve structure in a patient, such as the aortic valve.
1. A valve prosthesis comprising:
a support frame comprising a plurality of cells arranged to define a bottom edge of the support frame, a plurality of major peak portions opposite the bottom edge, and at least one minor peak portion disposed longitudinally intermediate the bottom edge and the plurality of major peak portions configured to allow access to and prevent obstruction to the ostia of the patient; and
a membrane attached to the support frame, wherein the membrane follows the major and/or minor peaks of the support frame.
2. The valve prosthesis of claim 1 , wherein the membrane comprises a first end portion corresponding to the bottom edge of the support frame, a plurality of membrane major peak portions corresponding to the plurality major peak portions of the support frame, and at least one membrane minor peak portion corresponding to the at least one minor peak portion of the support frame.
3. The valve prosthesis of claim 2 , wherein one or more membrane major peak portions of the plurality of membrane major peak portions are wrapped around corresponding one or more major peak portions of the plurality of major peak portions of the support frame to cover a part of an inner surface and a part of an outer surface of the support frame at the corresponding one or more major peak portions of the support frame.
4. The valve prosthesis of claim 3 , wherein one or more membrane minor peak portions of the at least one membrane minor peak portion are wrapped around corresponding one or more minor peak portions of the at least one minor peak portion of the support frame to cover a part of an inner surface and a part of an outer surface of the support frame at the corresponding one or more minor peak portions of the support frame.
5. The valve prosthesis of claim 1 , wherein the at least one minor peak portion is disposed at a lower axial distance from the bottom edge compared to the plurality of major peak portions.
6. The valve prosthesis of claim 1 , wherein membrane fabric of the membrane is formed from woven fiber.
7. The valve prosthesis of claim 6 , wherein the membrane fabric is formed by weaving fibers in a warp direction and a weft direction that are oriented transverse relative to each other.
8. The valve prosthesis of claim 7 , wherein the membrane fabric resists stretching in the warp direction and the weft direction of the fibers.
9. The valve prosthesis of claim 7 , wherein the membrane fabric stretches in one or more directions oblique to the warp direction or the weft direction of the fibers.
10. A valve prosthesis comprising:
a support frame comprising a plurality of cells arranged to define a bottom edge of the support frame, a plurality of major peak portions opposite the bottom edge, and at least one minor peak portion disposed longitudinally intermediate the bottom edge and the the plurality of major peak portion configured to allow access to and prevent obstruction to the ostia of the patient; and
a membrane attached to the support frame, wherein membrane fabric of the membrane is woven and comprises fibers extending in a warp direction and a weft direction that are oriented transverse relative to each other.
11. The valve prosthesis of claim 10 , wherein the membrane fabric resists stretching in the warp direction and the weft direction of the fibers.
12. The valve prosthesis of claim 10 , wherein the membrane fabric stretches in one or more directions oblique to the warp direction or the weft direction of the fibers.