Inflatable implant
Described is an inflatable implant suitable for placement in the human body and left there for an indeterminate and potentially lengthy period of time. The implant includes at least one bladder wall. The bladder wall will define at least one fillable volume and may form more than one independent fillable volumes. The wall and filler material may be selected to deliver treatment materials to the locale of the implant site or to remove amounts of harmful materials from such a region. The implant may, with an appropriate filler material or bladder wall material, be used in cooperation with an appropriate radio frequency (RF) source to cause the increase of a localized internal temperature and a resulting tissue change such as coagulation, ablation, or the like. Methods of using the implant are also described.
1. An inflatable, expandable implant suitable for implantation in a human body, comprising: a bladder comprising
a substantially non-elastic bladder wall defining a volume and having at least one bladder wall opening for introduction of filler material; and
an elastic bladder wall defining a volume and having at least one bladder wall opening for introduction of the filler material.
2. The implant of claim 1 , further comprising at least one closure for each of the bladder wall openings for maintaining the filler material within the volume after introduction of the filler material into the volume.
3. The implant of claim 1 , where the substantially non-elastic and elastic bladder walls comprise fabrics selected from the group consisting of woven fabric and non-woven fabric.
4. The implant of claim 1 , where the substantially non-elastic bladder wall comprises at least one member selected from the group consisting of polyethyleneterephthalate, polyvinylchloride, polyurethanes, polyolefins, polyamides, and fluoropolymers.
5. The implant of claim 1 , where the substantially non-elastic bladder wall comprises at least one fluoropolymer selected from the group consisting of polytetrafluoroethylene, poly(ethylene-chlorofluoroethylene), poly(fluorinated ethylene propylene), polyperfluoroalkoxy, polychlorotrifluoroethylene, polyvinylfluoride, polyvinylidenefluoride, and expanded polytetrafluoroethylene.
6. The implant of claim 1 , where the substantially non-elastic bladder wall comprises expanded polytetrafluoroethylene.
7. The implant of claim 1 further comprising the filler material.
8. The implant of claim 7 wherein the filler material is a filling liquid.
9. The implant of claim 8 wherein the filling liquid is selected from the group consisting of water, saline, and biocompatible liquids.
10. The implant of claim 7 wherein the filler material contains bioactive or chemi-active material.
11. The implant of claim 7 wherein the filler material comprises a reactive mixture adapted to react within the bladder volume.
12. The implant of claim 7 wherein the filler material comprises a member selected from the group consisting of elastic solids, viscoelastic solids, viscoelastic liquids, viscoelastic liquids comprising gel microparticles, viscous liquids, and their precursors.
13. The implant of claim 7 wherein the filler material comprises a copolymer of a first member selected from the group consisting of poly(ethylene glycol), poly(ethylene oxide), poly(vinyl alcohol), poly(ethylene-co-vinyl alcohol), poly(acrylic acid), poly(ethylene-co-acrylic acid), poly(ethyloxazoline), poly(vinyl pyrrolidone), poly(ethylene-co-vinyl pyrrolidone), poly(maleic acid), poly(ethylene-co-maleic acid), poly(acrylamide), and poly(ethylene oxide)-co-poly(propylene oxide) block copolymers and a second member having a strong nucleophile selected from the group consisting of a thiol or a group containing a thiol.