IP Library › Patent Application 16277248
Patent Application
App. No. 16/277,248

SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
16/277,248
Abstract

Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.

Claims (2)

1 - 34 . (canceled)

35 . A method of use of a pharmaceutical composition comprising benzyl N α -(tert-butoxycarbonyl)-1-methyl-D-tryptophanate to treat immunosuppression associated with HIV-1 infection in a subject in need thereof, comprising orally administering a sufficient amount of the composition to the subject in an appropriate pharmaceutical form or vehicle.

Assignments (2)
CHANGE OF NAME Recorded Jun 17, 2020
From: NEWLINK GENETICS CORPORATION
To: LUMOS PHARMA, INC.
Reel/Frame 052965/0558 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2020
From: MAUTINO, MARIO R.; KUMAR, SANJEEV; JAIPURI, FIROZ; WALDO, JESSE; POTTURI, HIMA; ZHUANG, HONG
To: NEWLINK GENETICS CORPORATION
Reel/Frame 052405/0681 →