Granted Patent B2

US 10,441,658 · App. 16/279,129 · Granted Oct 15, 2019

Abstract

Claims (5)

1. A method of reducing the precipitation of a polyquaternium compound and an anionic polymer in a composition ophthalmologically suitable for application to the eyes comprising such compounds, comprising the steps of:

i) providing from about 0.001% to about 0.5% of an anionic polymer having a weight average molecular weight of from about 250 to about 4,000,000 Daltons;

ii) adding an effective amount of an organic acid, salts thereof or mixtures thereof, such that the organic acid binds with the monomer units of the polyquaternium compound at at least a 1:1 molar ratio; and

iii) adding from about 10 ppm to about 1000 ppm of a polyquaternium compound having a weight average molecular weight of from about 150 to about 15,000 Daltons;

wherein the composition is substantially free of cationic oligomer compounds and precipitation inhibiting compounds.

Assignments (6)