IP Library Granted Patent US 10,918,724
Granted Patent B2
US 10,918,724 · App. 16/281,516 · Granted Feb 16, 2021

Dermocosmetic compositions including glycerol-sebacate

Inventors: Peter D. Gabriele (Frisco, TX); Jeremy J. Harris (Doylestown, PA); Carissa Smoot (Harleysville, PA); Charles Brendan Nicholson (Coopersburg, PA); Stephanie Reed (Conshohocken, PA); Ryan R. Smalley (Lansdale, PA)
Assignee: THE SECANT GROUP, LLC
A61K47/34A61K8/375A61K8/85A61K9/7023A61K45/06A61P17/02A61Q19/00A61L27/34A61L27/54A61L2430/20A61Q19/08
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Quick Facts
Patent No.
US 10,918,724
App. No.
16/281,516
Granted
Feb 16, 2021
Kind
B2
Abstract

A method of forming a skin care product includes combining at least one additive including at least one active ingredient with at least one glycerol-sebacate component having repeating units of (glycerol sebacate), water, a co-solvent, and at least one of an emulsifier, a surfactant, and a bodying agent to form the skin care product. A dermocosmetic composition includes at least one additive including at least one active ingredient and at least one glycerol-sebacate component having repeating units of (glycerol sebacate). A method of skin care includes applying a dermocosmetic composition to a skin surface.

Claims (17)

1. A method of skin care comprising:

applying a dermocosmetic composition to a skin surface, the dermocosmetic composition comprising:

at least one additive comprising at least one active ingredient; and

at least one glycerol-sebacate component having repeating units of (glycerol sebacate);

wherein the at least one additive is covalently attached to the glycerol-sebacate component; and

wherein the applying comprises applying the dermocosmetic composition as a dermal patch to the skin surface based on Langer's lines.

2. The method of claim 1 , wherein the at least one additive is selected from the group consisting of cholesterol, a small chain fatty acid, a glycolic acid, a lactic acid, arbutin, vitamin B, vitamin D, estrogen, an antioxidant, lauric acid, an amino acid, magnesium oxide, decanoic acid, retinoic acid, nicotinamide, B-carotene, resveratrol, a natural light-active compound, a radical-active compound, and combinations thereof.

3. The method of claim 1 , wherein the at least one active ingredient is selected from the group consisting of an alpha-hydroxy acid, a beta-hydroxy acid, salicylic acid, citric acid, a curcuminoid, hydroquinone, kojic acid, retinol, L-ascorbic acid, hyaluronic acid, copper peptide, alpha-lipoic acid, niacinamide, a ceramide, a peptide, vitamin E, dimethylaminoethanol, and combinations thereof.

4. The method of claim 1 , wherein the at least one glycerol-sebacate component is selected from the group consisting of poly(glycerol sebacate), oligomeric (glycerol sebacate), and thermoset poly(glycerol sebacate) flour.

5. The method of claim 1 , wherein the dermocosmetic composition further comprises water, a co-solvent, and a component selected from the group consisting of an emulsifier, a surfactant, a bodying agent, and combinations thereof.

6. The method of claim 1 , wherein the at least one glycerol-sebacate component is applied for the purpose of altering an expression of at least one gene in skin after application of the dermocosmetic composition to the skin surface.

7. A method of skin care comprising:

providing a dermocosmetic composition comprising at least one glycerol-sebacate component having repeating units of (glycerol sebacate), the dermocosmetic composition having an effective amount of the at least one glycerol-sebacate component to alter an expression of at least one gene in skin after application of the dermocosmetic composition to the skin surface; and

applying the dermocosmetic composition to a surface of the skin such that the expression of the at least one gene in the skin is altered by the at least one glycerol-sebacate component;

wherein the dermocosmetic composition further comprises at least one additive comprising at least one active ingredient;

wherein the at least one additive is covalently attached to the glycerol-sebacate component; and

wherein the applying comprises applying the dermocosmetic composition as a dermal patch to the skin surface based on Langer's lines.

Assignments (2)
SECURITY INTEREST Recorded May 28, 2021
From: THE SECANT GROUP, LLC
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 056421/0952 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 21, 2019
From: GABRIELE, PETER D.; HARRIS, JEREMY J.; SMOOT, CARISSA; NICHOLSON, CHARLES BRENDAN; REED, STEPHANIE; SMALLEY, RYAN R.
To: THE SECANT GROUP, LLC
Reel/Frame 048397/0315 →
Continuity (2)
Provisional Application 62633380 · Feb 21, 2018
Related Publication 20190255180A1 · Aug 22, 2019