IP Library Granted Patent US 10,940,626
Granted Patent B2
US 10,940,626 · App. 16/290,458 · Granted Mar 9, 2021

Manufacturing of small film strips

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Quick Facts
Patent No.
US 10,940,626
App. No.
16/290,458
Granted
Mar 9, 2021
Kind
B2
Abstract

The present invention relates to methods for forming films. In particular, the present invention relates to the formation of films on a substrate via the use of individual pumps to deposit individual wet film products onto a substrate.

Claims (44)

1. A method of forming a plurality of individual film products, comprising the steps of:

(a) providing a reservoir housing a film forming matrix;

(b) providing a plurality of individual volumetric pumps;

(c) providing a feed line which connects said reservoir to said plurality of individual volumetric pumps; wherein each of said individual volumetric pumps in said plurality of individual volumetric pumps is connected to said feed line;

(d) providing a substrate;

(e) feeding film forming matrix from said reservoir via said feed line to said plurality of individual volumetric pumps; and

(f) dispensing film forming matrix from said plurality of individual volumetric pumps

to form lanes of individual wet film products on said substrate.

2. The method of claim 1 , wherein each of said individual volumetric pumps dispenses about 4 microliters to about 250 microliters per stroke.

3. The method of claim 1 , further comprising the step:

(g) drying said individual wet film products to form dried individual film products.

4. The method of claim 1 , wherein each of said individual volumetric pumps dispenses about 3 microliters to about 250 microliters per pumping cycle.

5. The method of claim 1 , wherein each of said individual volumetric pumps dispenses about 250 microliters or less per pumping cycle.

6. The method of claim 1 , wherein each of said individual volumetric pumps dispenses from about 30 microliters to about 10 milliliters per pumping cycle.

7. The method of claim 1 , wherein the film forming matrix comprises an active.

8. An apparatus for forming a plurality of individual film products, comprising:

(a) a reservoir housing a film forming matrix;

(b) a plurality of individual volumetric pumps;

(c) a feed line which connects said reservoir to said plurality of individual volumetric pumps; and

(d) a substrate;

wherein each of said individual volumetric pumps in said plurality of individual volumetric pumps is connected to said feed line;

wherein film forming matrix is fed from said reservoir to said plurality of individual volumetric pumps via said feed line; and

wherein said plurality of individual volumetric pumps dispenses film forming matrix to form lanes of individual wet film products on said substrate.

9. The apparatus of claim 8 , wherein each of said individual volumetric pumps dispenses about 4 microliters to about 250 microliters per stroke.

10. The apparatus of claim 8 , wherein each of said individual volumetric pumps dispenses about 3 microliters to about 250 microliters per pumping cycle.

11. The apparatus of claim 8 , wherein each of said individual volumetric pumps dispenses about 250 microliters or less per pumping cycle.

12. The apparatus of claim 8 , wherein each of said individual volumetric pumps dispenses from about 30 microliters to about 10 milliliters per pumping cycle.

13. The apparatus of claim 8 , wherein the film forming matrix comprises an active.

14. A method of forming a plurality of individual film patches, comprising the steps of:

(a) providing a substrate comprising a sheet of dissolvable polymeric material, said sheet having a top surface;

(b) providing a reservoir housing a film forming matrix;

(c) providing a substrate;

(d) providing a plurality of individual volumetric pumps;

(e) providing a feed line which connects said reservoir to said plurality of individual volumetric pumps; wherein each of said individual volumetric pumps in said plurality of individual volumetric pumps is connected to said feed line;

(f) feeding film forming matrix from said reservoir via said feed line to said plurality of individual volumetric pumps;

(g) dispensing said film forming matrix from said plurality of individual volumetric pumps

to form lanes of individual wet film products on said top surface of said sheet; and

(h) drying said individual wet film products to form a plurality of multi-layer film patches comprising a first layer comprising said sheet and a second layer comprising a dried film product.

15. The method of claim 14 , wherein said feeding step in (f) and said dispensing step in (g) are repeated to form said lanes of said individual wet film products on said substrate.

16. The method of claim 14 , wherein each of said individual volumetric pumps dispenses about 3 microliters to about 250 microliters per pumping cycle.

17. The method of claim 14 , wherein each of said individual volumetric pumps dispenses about 250 microliters or less per pumping cycle.

18. The method of claim 14 , wherein each of said individual volumetric pumps dispenses from about 30 microliters to about 10 milliliters per pumping cycle.

19. The method of claim 14 , wherein said dispensing in step (g) comprises dispensing a predetermined amount of said film forming matrix to form lanes of individual wet film products on said top surface of said sheet.

20. The method of claim 14 , wherein said film forming matrix is a wet film forming matrix comprising a polymeric material and an active.

Assignments (7)
RELEASE OF SECURITY INTEREST Recorded May 13, 2026
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: AQUESTIVE THERAPEUTICS, INC.
Reel/Frame 075646/0258 →
SECURITY INTEREST Recorded May 12, 2026
From: AQUESTIVE THERAPEUTICS, INC.
To: OAKTREE FUND ADMINISTRATION, LLC, AS ADMINISTRATIVE AGENT
Reel/Frame 075561/0782 →
SECURITY INTEREST Recorded Nov 2, 2023
From: AQUESTIVE THERAPEUTICS, INC.
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 065446/0494 →
RELEASE OF SECURITY INTEREST Recorded Nov 1, 2023
From: U.S. BANK TRUST COMPANY NATIONAL ASSOCIATION (AS SUCCESSOR IN INTEREST TO U.S BANK NATIONAL ASSOCIATION)
To: AQUESTIVE THERAPEUTICS, INC.
Reel/Frame 065426/0642 →
CHANGE OF NAME Recorded Sep 5, 2019
From: MONOSOL RX, LLC
To: AQUESTIVE THERAPEUTICS, INC.
Reel/Frame 050287/0009 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 5, 2019
From: BOGUE, BEUFORD A.
To: MONOSOL RX, LLC
Reel/Frame 050276/0875 →
SECURITY INTEREST Recorded Jul 15, 2019
From: AQUESTIVE THERAPEUTICS, INC.
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 049758/0082 →