IP Library Granted Patent US 11,008,583
Granted Patent B2
US 11,008,583 · App. 16/311,377 · Granted May 18, 2021

Increasing plant growth and yield by using an ADP-glucose pyrophosphorylase sequence

Inventor: Benjamin Neil Gray (Chapel Hill, NC)
Assignee: Benson Hill, Inc.
C12N15/8261C12N9/1241C12Y207/07027
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Quick Facts
Patent No.
US 11,008,583
App. No.
16/311,377
Granted
May 18, 2021
Kind
B2
Abstract

Compositions and methods for improving plant growth are provided herein. Polynucleotides encoding ADP-glucose pyrophosphorylase small subunit (AGPaseSS) proteins, polypeptides encompassing AGPaseSS proteins, and expression constructs for expressing genes of interest whose expression may improve agronomic properties including but not limited to crop yield, biotic and abiotic stress tolerance, and early vigor, plants comprising the polynucleotides, polypeptides, and expression constructs, and methods of producing transgenic plants are also provided.

Claims (16)

1. A method for increasing crop yield comprising transforming a plant with at least one ADP-glucose pyrophosphorylase small subunit (AGPaseSS) protein-encoding sequence, wherein said AGPaseSS protein-encoding sequence comprises SEQ ID NO:1 or 2, or encodes a protein comprising SEO ID NO:3.

2. A plant having stably incorporated into its genome a promoter that drives expression in a plant operably linked to an AGPaseSS protein-encoding sequence, wherein said promoter is heterologous to said AGPaseSS protein-encoding sequence, and wherein said AGPaseSS protein-encoding sequence comprises SEQ ID NO: 1 or 2, or encodes a protein comprising SEQ ID NO: 3.

3. Transformed seed of the plant of claim 2 .

4. The plant of claim 2 wherein said plant is a monocot.

5. The plant of claim 4 wherein said plant is from the genus Zea, Oryza, Triticum, Sorghum, Secale, Eleusine, Setaria, Saccharum, Miscanthus, Panicum, Pennisetum, Megathyrsus, Cocos, Ananas, Mus a, Elaeis, Avena , or Hordeum.

6. The plant of claim 2 wherein said plant is a dicot.

7. The plant of claim 6 wherein said plant is from the genus Glycine, Brassica, Medicago, Helianthus, Carthamus, Nicotiana, Solanum, Gossypium, Ipomoea, Manihot, Coea, Citrus, Theobroma, Camellia, Persea, Ficus, Psidium, Mangifera, Olea, Carica, Anacardium, Macadamia, Prunus, Beta, Populus , or Eucalyptus.

8. The method of claim 1 , wherein said AGPaseSS protein-encoding sequence is expressed from a promoter that comprises SEQ ID NO:8.

9. The plant of claim 2 , wherein said promoter that drives expression in a plant comprises SEQ ID NO:8.

10. A DNA construct comprising, in operable linkage,

a. A promoter that is functional in a plant cell and,

b. A nucleic acid sequence encoding an AGPaseSS protein, wherein said nucleic acid sequence encoding the AGPaseSS protein comprises SEQ ID No: 1 or 2, or encodes a protein that comprises SEQ ID NO:3.

11. The DNA construct of claim 10 , wherein said promoter that is functional in a plant cell comprises SEQ ID NO:8.

12. A method for increasing crop yield comprising modulating the expression of at least one AGPaseSS protein-encoding sequence in a plant, wherein said AGPaseSS protein-encoding sequence comprises SEQ ID NO:1 or 2, or encodes a protein comprising SEQ ID NO:3.

13. The method of claim 12 wherein said modulating the expression comprises increasing the expression of at least one AGPaseSS protein-encoding sequence in a plant.

14. The DNA construct of claim 10 wherein said promoter is heterologous to said nucleic acid sequence encoding an AGPaseSS protein.

Assignments (8)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2025
From: BENSON HILL, INC.; BENSON HILL HOLDINGS, INC.; BENSON HILL FRESH, LLC; BENSON HILL SEEDS HOLDING, INC.; BHB HOLDINGS, LLC; J&J SOUTHERN FARMS, INC.; BENSON HILL SEEDS, INC.
To: CONFLUENCE GENETICS, LLC
Reel/Frame 071578/0432 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 30, 2025
From: BENSON HILL, INC.; BENSON HILL HOLDINGS, INC.; BENSON HILL FRESH, LLC; BENSON HILL SEEDS HOLDING, INC.; BENSON HILL SEEDS, INC.; BHB HOLDINGS, LLC; J&J SOUTHERN FARMS, LLC
To: CONFLUENCE GENETICS, LLC
Reel/Frame 071982/0368 →
RELEASE OF SECURITY INTEREST Recorded Feb 14, 2024
From: AVENUE VENTURE OPPORTUNITIES FUND, L.P.
To: BENSON HILL HOLDINGS, INC.
Reel/Frame 066460/0961 →
SECURITY INTEREST Recorded Jan 18, 2023
From: BENSON HILL, INC.
To: AVENUE VENTURE OPPORTUNITIES FUND, L.P.
Reel/Frame 062404/0643 →
RELEASE OF SECURITY INTEREST Recorded Oct 4, 2021
From: VENTURE LENDING & LEASING VIII, INC.; VENTURE LENDING & LEASING IX, INC.
To: BENSON HILL, INC.
Reel/Frame 057696/0136 →
CHANGE OF NAME Recorded Jun 30, 2020
From: BENSON HILL BIOSYSTEMS, INC.
To: BENSON HILL, INC.
Reel/Frame 053086/0406 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 30, 2020
From: GRAY, BENJAMIN NEIL
To: BENSON HILL BIOSYSTEMS, INC.
Reel/Frame 053086/0228 →
SECURITY INTEREST Recorded Feb 5, 2020
From: BENSON HILL, INC.
To: VENTURE LENDING & LEASING VIII, INC.; VENTURE LENDING & LEASING IX, INC.
Reel/Frame 051830/0284 →
Continuity (2)
Provisional Application 62353399 · Jun 22, 2016
Related Publication 20200308597A1 · Oct 1, 2020