IP Library Granted Patent US 11,278,526
Granted Patent B2
US 11,278,526 · App. 16/337,292 · Granted Mar 22, 2022

Compounds and methods for treating lupus

Inventors: Fiona Lorraine Scott (San Diego, CA); Kristen R. Taylor Meadows (San Diego, CA); Robert Peach (San Diego, CA)
Assignee: RECEPTOS LLC
A61K31/4245A61P37/02
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,278,526
App. No.
16/337,292
Granted
Mar 22, 2022
Kind
B2
Abstract

Methods for treatment of systemic lupus erythematosus (SLE” or “Lupus”) by administration of a modulator of sphingosine-1-phosphate receptor subtype 1 (S1P1), as well as compositions and methods related to the same, wherein such S1P1 modulators have the following general structure and wherein X and Y are as defined herein.

Claims (3)

1. A method for treating systemic lupus erythematosus in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound having the following structure, or a pharmaceutically acceptable salt, homolog, hydrate or solvate thereof:

2. The method of claim 1 , wherein the compound is in the form of a racemic mixture.

3. The method of claim 1 , wherein the compound is in the form of an isolated optical isomer.

Assignments (3)
CHANGE OF ADDRESS OF ASSIGNEE Recorded May 4, 2024
From: RECEPTOS LLC
To: RECEPTOS LLC
Reel/Frame 068258/0194 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2021
From: SCOTT, FIONA LORRAINE; MEADOWS, KRISTEN R. TAYLOR; PEACH, ROBERT
To: CELGENE INTERNATIONAL II SÀRL
Reel/Frame 058339/0609 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2021
From: CELGENE INTERNATIONAL II SÀRL
To: RECEPTOS LLC
Reel/Frame 055192/0805 →
Continuity (2)
Provisional Application 62401762 · Sep 29, 2016
Related Publication 20190224172A1 · Jul 25, 2019