IP Library Granted Patent US 11,920,126
Granted Patent B2
US 11,920,126 · App. 16/363,052 · Granted Mar 5, 2024

Bio-manufacturing process

Inventor: Damen Schaak (Clifton Park, NY)
Assignee: Ecovative Design LLC
C12N11/02A01G18/10A23K10/18A23K40/30C12N1/00C12N1/02C12N1/14C12N1/205C12N9/80C12N9/88C12N11/14C12N15/00C12N15/52C12N15/746C12N15/76C12N15/80C12R2001/07C12R2001/125C12R2001/465C12Y305/01041C12Y402/01001
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Quick Facts
Patent No.
US 11,920,126
App. No.
16/363,052
Granted
Mar 5, 2024
Kind
B2
Abstract

The process of making a biocomposite material utilize a bacterial species and a fungal species in an agricultural feedstock composed of a substrate of non-nutrient discrete particles and a nutrient material wherein the bacterial species imparts mechanical properties to the biocomposite material and the fungal species binds the biocomposite material. Both bacterium and fungus can be genetically engineered to produce desired properties within the microbial communities.

Claims (29)

1. A process comprising:

obtaining a feedstock including non-nutrient discrete particles, a nutrient material and at least one native microbial species;

isolating said at least one native microbial species from said feedstock;

subjecting said isolated native microbial species to genetic processing to transform said native microbial species into a genetically engineered microbial species having predetermined characteristics;

thereafter returning said genetically engineered microbial species into said feedstock; and

cohabitating at least one filamentous fungal species with said genetically engineered microbial species in the feedstock, thereby producing a biocomposite material with desired properties.

2. The process of claim 1 , wherein said native microbial species is at least one of Bacillus spp. and Streptomyces spp.

3. The process of claim 2 , wherein at least one of said characteristics is producing a bio-film containing poly-gamma-glutamic acid in said feedstock, producing natamycin in said feedstock and producing an antifungal protein (AFP1) native to Streptomyces tendae in said feedstock.

4. The process of claim 2 , wherein said native microbial species is Bacillus spp.

5. The process of claim 4 , wherein at least one of said characteristics is producing a bio-film containing poly-gamma-glutamic acid in said feedstock.

6. The process of claim 4 , wherein at least one of said characteristics is producing natamycin in said feedstock.

7. The process of claim 4 , wherein at least one of said characteristics is producing an antifungal protein (AFP1) native to Streptomyces tendae in said feedstock.

8. The process of claim 2 , wherein said native microbial species is Streptomyces spp.

9. The process of claim 8 , wherein said native microbial species is Streptomyces natalensis.

10. The process of claim 9 , wherein at least one of said characteristics is producing a bio-film containing poly-gamma-glutamic acid in said feedstock.

11. The process of claim 9 , wherein at least one of said characteristics is producing natamycin in said feedstock.

12. The process of claim 9 , wherein at least one of said characteristics is producing an antifungal protein (AFP1) native to Streptomyces tendae in said feedstock.

13. The process of claim 8 , wherein said native microbial species is Streptomyces tendae.

14. The process of claim 13 , wherein at least one of said characteristics is producing a bio-film containing poly-gamma-glutamic acid in said feedstock.

15. The process of claim 13 , wherein at least one of said characteristics is producing natamycin in said feedstock.

16. The process of claim 13 , wherein at least one of said characteristics is producing an antifungal protein (AFP1) native to Streptomyces tendae in said feedstock.

17. The process of claim 8 , wherein said native microbial species is Streptomyces alboniger.

18. The process of claim 17 , wherein at least one of said characteristics is producing a bio-film containing poly-gamma-glutamic acid in said feedstock.

19. The process of claim 17 , wherein at least one of said characteristics is producing natamycin in said feedstock.

20. The process of claim 17 , wherein at least one of said characteristics is producing an antifungal protein (AFP1) native to Streptomyces tendae in said feedstock.

21. The process of claim 1 , wherein obtaining comprises obtaining the feedstock further including the at least one filamentous fungal species.

22. The process of claim 1 , further comprising subjecting said filamentous fungal species to genetic processing to transform said filamentous fungal species into a genetically engineered filamentous fungal species having predetermined characteristics.

23. The process of claim 22 , wherein returning further comprises returning said genetically engineered filamentous fungal species into said feedstock.

24. The process of claim 1 , wherein said desired properties is at least one of mechanical properties, morphological properties, and antimicrobial properties.

Assignments (2)
CHANGE OF NAME Recorded Aug 13, 2024
From: ECOVATIVE DESIGN LLC
To: ECOVATIVE LLC
Reel/Frame 068569/0703 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 25, 2019
From: SCHAAK, DAMEN
To: ECOVATIVE DESIGN LLC
Reel/Frame 048686/0048 →
Continuity (3)
Provisional Application 62649175 · Mar 28, 2018
Related Publication 20190322997A1 · Oct 24, 2019
Related Publication 20210317433A9 · Oct 14, 2021
Cited By (1)
US 12,464,989