IP Library Granted Patent US 10,765,478
Granted Patent B2
US 10,765,478 · App. 16/363,655 · Granted Sep 8, 2020

Picosecond optical radiation systems and methods of use

Inventors: Rafael Armando Sierra (Palmer, MA); Mirko Georgiev Mirkov (Chelmsford, MA)
Assignee: CYNOSURCE, LLC
A61B18/203A61N5/0616H01S3/0627H01S3/08018H01S3/094076H01S3/1024H01S3/1106H01S3/1109H01S3/1121A61B2018/0047A61N2005/067H01S3/0092H01S3/08054H01S3/093H01S3/094038H01S3/094084H01S3/107H01S3/1611H01S3/1623H01S3/1633H01S3/1643H01S3/1673
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,765,478
App. No.
16/363,655
Granted
Sep 8, 2020
Kind
B2
Abstract

Methods, systems and apparatus are disclosed for delivery of pulsed treatment radiation by employing a pump radiation source generating picosecond pulses at a first wavelength, and a frequency-shifting resonator having a lasing medium and resonant cavity configured to receive the picosecond pulses from the pump source at the first wavelength and to emit radiation at a second wavelength in response thereto, wherein the resonant cavity of the frequency-shifting resonator has a round trip time shorter than the duration of the picosecond pulses generated by the pump radiation source. Methods, systems and apparatus are also disclosed for providing beam uniformity and a sub-harmonic resonator.

Claims (29)

1. An apparatus for delivery of pulsed treatment radiation comprising:

a pump radiation source generating pumping pulses at a first wavelength, and

a wavelength-shifting resonator having a lasing medium and resonant cavity configured to receive the pumping pulses from the pump radiation source at the first wavelength and to emit pulsed treatment radiation at a second wavelength with a pulse duration shorter than the pulse duration of the pump radiation source in response thereto,

wherein the resonant cavity of the wavelength-shifting resonator has a round trip time shorter than the duration of the pumping pulses.

2. The apparatus of claim 1 , wherein the wavelength-shifting resonator operates without use of a modelocker or a Q-switch.

3. The apparatus of claim 1 , wherein the wavelength-shifting resonator emits a subnanosecond pulse.

4. The apparatus of claim 1 , wherein the wavelength-shifting resonator has a cavity length less than 10 millimeters.

5. The apparatus of claim 1 , wherein the lasing medium of the wavelength-shifting resonator comprises a neodymium-doped crystal.

6. The apparatus of claim 1 , wherein the lasing medium of the wavelength-shifting resonator comprises a solid state crystal medium selected from the group consisting of neodymium-doped yttrium-aluminum garnet (Nd:YAG) crystals, neodymium-doped pervoskite (Nd:YAP or Nd:YAlO 3 ) crystals, neodymium-doped yttrium-lithium-fluoride (Nd:YAF) crystals, and neodymium-doped, vanadate (Nd:YVO 4 ) crystals.

7. The apparatus of claim 1 , further comprising a polarizer embedded within the resonant cavity of the wavelength-shifting resonator.

8. The apparatus of claim 1 , wherein the lasing medium of the wavelength-shifting resonator is a polarizing medium.

9. The apparatus of claim 1 , further comprising a frequency-doubling crystal.

10. The apparatus of claim 9 , wherein the frequency-doubling crystal comprises a nonlinear crystal material.

11. The apparatus of claim 9 , wherein the frequency-doubling waveguide comprises a lithium triborate (LiB 3 O 5 ) material or a KTP material.

12. The apparatus of claim 1 , wherein the pump radiation source is a mode-locked laser.

13. The apparatus of claim 12 , wherein the mode-locked laser comprises an alexandrite laser.

14. The apparatus of claim 12 , wherein the mode-locked laser generates pulsed laser energy having at least about 100 mJ/pulse.

15. The apparatus of claim 1 , further comprising a treatment beam delivery system configured to apply a treatment beam to a patient's skin.

16. The apparatus of claim 1 , wherein the wavelength-shifting resonator emits a laser energy having at least about 100 mJ/pulse.

17. A method of delivering pulsed treatment radiation comprising:

generating pumping pulses, using a pump radiation source, wherein one or more pumping pulses are at a first wavelength and a first pulse duration;

transmitting the pumping pulses to a resonant cavity of a wavelength-shifting resonator; and

emitting pulsed treatment radiation at a second wavelength from the wavelength-shifting resonator, wherein one or more pulses of the pulsed treatment radiation have a second pulse duration, the second pulse duration shorter than first pulse duration,

wherein the resonant cavity has a round trip time shorter than the duration of the pumping pulses.

18. The method of claim 17 further comprising applying a treatment beam to a patient.

19. The method of claim 17 wherein the pulsed treatment radiation comprises a subnanosecond pulse.

20. The method of claim 17 further comprising applying one or more subnanosecond pulses to a patient.

21. The method of claim 17 further comprising applying one or more subnanosecond pulses to a tattoo or a region of skin pigmentation.

22. The method of claim 17 , wherein the wavelength-shifting resonator emits a laser energy having at least about 100 mJ/pulse.

Assignments (8)
RELEASE OF SECURITY INTEREST Recorded Mar 1, 2024
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066723/0227 →
TERMINATION AND RELEASE OF PATENTS Recorded Feb 29, 2024
From: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
To: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
Reel/Frame 066707/0957 →
ABL NOTICE AND CONFIRMATION OF GRANT OFSECURITY INTEREST IN PATENTS Recorded Jan 12, 2024
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: UBS AG, STAMFORD BRANCH, AS COLLATERAL AGENT
Reel/Frame 066222/0937 →
CHANGE OF NAME Recorded Jul 20, 2020
From: CYNOSURE, INC.
To: CYNOSURE, LLC
Reel/Frame 053249/0071 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2020
From: SIERRA, RAFAEL ARMANDO; MIRKOV, MIRKO GEORGIEV
To: CYNOSURE, INC.
Reel/Frame 053248/0892 →
NOTICE AND CONFIRMATION OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Jan 7, 2020
From: CYNOSURE, LLC; PALOMAR MEDICAL TECHNOLOGIES, LLC
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 051496/0579 →
RELEASE OF SECURITY INTEREST IN PATENT RIGHTS Recorded Dec 30, 2019
From: BANK OF AMERICA, N.A.
To: CYNOSURE, LLC
Reel/Frame 051447/0536 →
SECURITY INTEREST Recorded Oct 14, 2019
From: HOLOGIC, INC.; CYNOSURE, LLC; CYTYC CORPORATION; FAXITRON BIOPTICS, LLC; FOCAL THERAPEUTICS, INC.; GEN-PROBE INCORPORATED
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 050719/0701 →