Devices and methods for left atrial appendage closure
Closure devices and methods are provided for ligating tissue, such as the left atrial appendage. Generally, the closure devices include an elongate body, a snare loop assembly comprising a snare and a suture loop, and a shuttle connected to the snare and releasably coupled to the elongate body and retractable therein. In some variations, the shuttle may be configured to fit into the lumen. In other variations, a handle may be attached to the elongate body, and the handle may comprise a track and a snare control coupled to the track. The handle may be configured to release the shuttle from the elongate body and allow movement of the snare control along the track to retract the snare loop and the shuttle into a lumen of the elongate body.
1. A device for closing a target tissue comprising:
an elongate body comprising a lumen therethrough;
a snare loop assembly comprising a snare and a suture loop releasably coupled to the snare, the snare loop assembly extending at least partially from the elongate body, wherein the snare comprises a moveable proximal end and a distal end releasably coupled to the elongate body, wherein the device comprises a first configuration in which the distal end of the snare is coupled to the elongate body and the snare forms a loop, and a second configuration in which the distal end of the snare is released from the elongate body and the snare is not looped;
a shuttle coupled to the distal end of the snare, wherein the shuttle releasably couples the distal end of the snare to the elongate body; and
a handle configured to retract the distal end of the snare into a lumen of the elongate body after the distal end is released.
2. The device of claim 1 , wherein the shuttle fixedly couples the distal end of the snare to the elongate body in the first configuration, and wherein the device further comprises a third configuration in which the shuttle is positioned at least partially within the lumen.
3. The device of claim 1 , wherein the shuttle has a maximum dimension that is less than a diameter of the lumen.
4. The device of claim 1 , wherein the elongate body comprises an approximately L-shaped recess in a side wall of the elongate body.
5. The device of claim 4 , wherein a distal portion of the snare is positioned in the recess when the distal end of the snare is coupled to the elongate body.
6. The device of claim 1 , wherein the distal end is coupled to a side wall of the elongate body in the first configuration.
7. The device of claim 6 , wherein the elongate body comprises a tip, and wherein the distal end is coupled to a side wall of the tip in the first configuration.
8. The device of claim 1 , wherein the distal end is coupled to the elongate body outside of the lumen in the first configuration.
9. A device for closing a target tissue comprising:
an elongate body comprising a lumen therethrough;
a snare loop assembly comprising a snare and a suture loop releasably coupled to the snare, the snare loop assembly extending at least partially from the elongate body, wherein the snare comprises a moveable proximal end and a distal end releasably coupled to the elongate body, wherein the device comprises a first configuration in which the distal end of the snare is coupled to the elongate body and the snare forms a loop, and a second configuration in which the distal end of the snare is released from the elongate body and the snare is not looped; and
a handle configured to retract the distal end of the snare into a lumen of the elongate body after the distal end is released,
wherein a retention member releasably couples the suture loop to the snare, and wherein the handle is configured to retract the entire retention member into the lumen after the distal end of the snare is released.
10. A device for closing a target tissue comprising:
an elongate body comprising a lumen therethrough;
a snare loop assembly comprising a snare and a suture loop releasably coupled to the snare, the snare loop assembly extending at least partially from the elongate body, wherein the snare comprises a moveable proximal end and a distal end releasably coupled to the elongate body, wherein the device comprises a first configuration in which the distal end of the snare is coupled to the elongate body and the snare forms a loop, and a second configuration in which the distal end of the snare is released from the elongate body and the snare is not looped; and
a handle configured to retract the distal end of the snare into a lumen of the elongate body after the distal end is released, wherein the handle comprises a track, a snare control coupled to the track, and a lock configured to limit movement of the snare control along the track.
11. The device of claim 10 , wherein the handle further comprises a release assembly configured to release the distal end of the snare from the elongate body and allow movement of the snare control along the track.
12. The device of claim 10 , wherein the track comprises a first portion and a second portion, and the lock limits movement of the snare control along the second portion of the track.
13. The device of claim 10 , wherein the lock is releasably coupled to the track.
14. A device for closing a target tissue comprising:
an elongate body comprising a lumen therethrough;
a snare loop assembly comprising a snare and a suture loop releasably coupled to the snare, the snare loop assembly extending at least partially from the elongate body; and
a shuttle coupled to a distal portion of the snare and releasably coupled to the elongate body, wherein the shuttle comprises a configuration to fit into the lumen, and wherein the device comprises a first configuration in which the shuttle is coupled to the elongate body and the snare forms a loop, and a second configuration in which the shuttle is released from the elongate body and the snare is not looped.
15. The device of claim 14 , wherein the shuttle is fixedly coupled to the elongate body in the first configuration, and the device comprises a third configuration in which the shuttle is positioned within the lumen.
16. The device of claim 14 , wherein the shuttle has a maximum dimension that is less than a diameter of the lumen.
17. The device of claim 14 , wherein the elongate body comprises an approximately L-shaped recess in a side wall of the elongate body.
18. The device of claim 17 , wherein the distal portion of the snare is positioned in the recess when the shuttle is coupled to the elongate body.
19. The device of claim 14 , wherein the shuttle comprises a snare lumen and a proximal portion of the snare lumen comprises an offset obround.
20. The device of claim 14 , wherein a distal portion of the elongate body comprises a corner chamfer.
21. The device of claim 20 further comprising a tip coupled to the distal portion of the elongate body wherein the tip comprises a tip lumen and a proximal portion of the tip comprises a tip chamfer.
22. The device of claim 21 , wherein the tip chamfer is 30 degrees and offset from the tip lumen.
23. The device of claim 14 further comprising a handle coupled to the elongate body, wherein the handle comprises a track, a snare control coupled to the track, and a lock configured to limit movement of the snare control along the track.
24. The device of claim 23 , wherein the lock is releasably coupled to the track.
25. The device of claim 14 , wherein the shuttle is coupled to a side wall of the elongate body in the first configuration.
26. The device of claim 25 , wherein the elongate body comprises a tip, and wherein the shuttle is coupled to a side wall of the tip in the first configuration.
27. The device of claim 14 , wherein the shuttle is coupled to the elongate body outside of the lumen in the first configuration.
28. A device for closing a target tissue comprising:
an elongate body comprising a lumen therethrough;
a snare loop assembly comprising a snare and a suture loop releasably coupled to the snare, the snare loop assembly extending at least partially from the elongate body; and
a shuttle coupled to a distal portion of the snare and releasably coupled to the elongate body, wherein the shuttle comprises a configuration to fit at least partially into the lumen, and wherein the device comprises a first configuration in which the shuttle is fixedly coupled to the elongate body outside the lumen and a second configuration in which the shuttle is positioned within the lumen.