Granted Patent B2

US 10,570,145 · App. 16/382,907 · Granted Feb 25, 2020

Inventors: Craig E. Masse (Cambridge, MA); Jeremy Robert Greenwood (Brooklyn, NY); Sayan Mondal (New York, NY); Scott D. Cowen (Cambridge, MA); Thomas H. McLean (Cambridge, MA)

Assignee: Nimbus Lakshimi, Inc.

C07D487/04A61P11/06A61P17/06A61P19/02A61P29/00A61P35/00A61P37/02C07D519/00

Abstract

Claims (51)

1. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

2. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

3. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

4. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

5. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

6. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

7. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

8. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

9. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

10. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

11. The compound of claim 1 , wherein said compound is selected from the group consisting of:

or a pharmaceutically acceptable salt thereof.

12. A pharmaceutical composition comprising a compound according to claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

13. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

14. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

15. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

16. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

17. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

18. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

19. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

20. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

21. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

22. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

23. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

24. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

25. A compound of the formula:

or a pharmaceutically acceptable salt thereof.

26. A pharmaceutical composition comprising a compound of the formula:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant, or vehicle.

Assignments (9)