Inverting thrombectomy apparatuses and methods of use
Inverting tube thrombectomy apparatus for removing clot that are configured to prevent compression of the apparatus that may separate the distal end of the apparatus from the clot and may make it difficult to advance the apparatus to engage with the clot, particularly in a tortious vessel. The apparatuses and methods of using them described herein may be adapted to prevent tension in the flexible tube that is rolling and inverting over the distal end of the inversion support catheter when capturing a clot. Also described herein are inverting tube thrombectomy apparatus that are configured to reload either automatically or manually within the vessel to capture additional clot material.
1. A method of removing a clot from a vessel, the method comprising:
advancing an inverting tube thrombectomy apparatus through a vessel until a distal end of the inverting tube thrombectomy apparatus is proximate to the clot, wherein the inverting tube thrombectomy apparatus comprises an inversion support catheter, a puller catheter slideable within a lumen of the inversion support catheter, and a flexible tube having a first end coupled at a distal end region of the puller catheter and a second end coupled to the inversion support catheter;
applying aspiration through a lumen in the puller catheter to hold the clot on distal end of the puller catheter;
pushing the inversion support catheter distally to form slack in the flexible tube; and
pulling the puller catheter proximally relative to the inversion support catheter to roll and invert the flexible tube over the distal end of the inversion support catheter and pull the clot into the inversion support catheter.
2. The method of claim 1 , wherein pushing the inversion support catheter distally to form slack in the flexible tube comprises expanding the flexible tube radially outward from the puller catheter.
3. The method of claim 1 , further comprising pulling the clot proximally though the lumen of the puller catheter.
4. The method of claim 3 , wherein pulling the clot proximally through the lumen of the puller catheter comprises aspirating the clot through the puller catheter.
5. The method of claim 3 , wherein pulling the clot proximally through the lumen of the puller catheter comprises using a wire to draw the clot proximally through the lumen of the puller catheter.
6. The method of claim 1 , further comprising reloading the inverting tube thrombectomy apparatus while still in the vessel.
7. The method of claim 6 , wherein reloading the inverting tube thrombectomy apparatus comprises advancing the puller catheter distally relative to the inversion support catheter.
8. The method of claim 7 , further comprising removing a second clot with the inverting tube thrombectomy apparatus.
9. The method of claim 6 , wherein advancing the puller catheter distally comprises releasing the puller catheter so that a bias advances the puller catheter distally.
10. The method of claim 1 , wherein pulling the puller catheter proximally comprises applying vacuum through the lumen of the puller catheter.
11. The method of claim 1 , wherein the inverting tube thrombectomy apparatus comprises an intermediate catheter.
12. A method of removing a clot from a vessel, the method comprising:
advancing an inverting tube thrombectomy apparatus through a vessel until a distal end of the inverting tube thrombectomy apparatus is proximate to the clot, wherein the inverting tube thrombectomy apparatus comprises an inversion support catheter, a puller catheter slideable within a lumen of the inversion support catheter, and a flexible tube having a first end coupled at a distal end region of the puller catheter and a second end coupled to the inversion support catheter;
applying aspiration through a lumen of the puller catheter to hold the clot on a distal end of the puller catheter;
pushing the inversion support catheter distally to expand the flexible tube radially outward;
pulling the puller catheter proximally while advancing the inversion support catheter distally to roll and invert the flexible tube over the distal end of the inversion support catheter and pull the clot into the inversion support catheter; and
pulling the clot proximally though the lumen of the puller catheter.
13. The method of claim 12 , wherein pulling the clot proximally through the lumen of the puller catheter comprises aspirating the clot through the puller catheter.
14. The method of claim 12 , wherein pulling the clot proximally through the lumen of the puller catheter comprises using a wire to draw the clot proximally through the lumen of the puller catheter.
15. The method of claim 12 , further comprising reloading the inverting tube thrombectomy apparatus while still in the vessel.
16. The method of claim 15 , wherein reloading the inverting tube thrombectomy apparatus comprises advancing the puller catheter distally relative to the inversion support catheter.
17. The method of claim 16 , wherein advancing the puller catheter distally comprises releasing the puller catheter so that a bias advances the puller catheter distally.
18. The method of claim 15 , further comprising removing a second clot with the inverting tube thrombectomy apparatus.
19. The method of claim 12 , wherein pulling the puller catheter proximally comprises applying vacuum through the lumen of the puller catheter as the puller catheter is pulled proximally.
20. The method of claim 12 , wherein the inverting tube thrombectomy apparatus comprises an intermediate catheter.