IP Library Granted Patent US 10,675,280
Granted Patent B2
US 10,675,280 · App. 16/412,009 · Granted Jun 9, 2020

Treating sexual desire disorders with flibanserin

Inventors: Franco Borsini (Baden Württemberg, DE); Kenneth Robert Evans (Toronto, CA)
Assignee: Sprout Pharmaceuticals, Inc.
A61K31/496
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Quick Facts
Patent No.
US 10,675,280
App. No.
16/412,009
Granted
Jun 9, 2020
Kind
B2
Abstract

The invention relates to the use of flibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.

Claims (25)

1. A method of treating a female hypoactive sexual desire disorder in a human adult patient, comprising orally administering a therapeutically effective amount of flibanserin to the patient to treat the female hypoactive sexual desire disorder.

2. The method according to claim 1 , wherein the amount administered is between about 0.1 mg and 400 mg per day of flibanserin.

3. The method according to claim 1 , wherein the amount administered is between about 1 mg and 300 mg per day of flibanserin.

4. The method according to claim 1 , wherein the amount administered is in a dosage unit containing between about 0.01 mg and 100 mg of flibanserin.

5. The method according to claim 1 , wherein the amount administered is in a dosage unit containing about 100 mg.

6. A method of treating a female hypoactive sexual desire disorder in a human adult patient, comprising orally administering a tablet comprising a therapeutically effective amount of flibanserin to the patient to treat the female hypoactive sexual desire disorder.

7. The method according to claim 6 , wherein the amount administered is between about 0.1 mg and 400 mg per day of flibanserin.

8. The method according to claim 6 , wherein the tablet comprises about 0.01 mg to 100 mg of flibanserin.

9. The method according to claim 6 , wherein the tablet comprises about 100 mg flibanserin.

10. The method according to claim 6 , wherein the tablet further comprises one or more excipients or carriers.

11. The method according to claim 10 , wherein the one or more excipients or carriers comprise at least one inert diluent.

12. The method according to claim 11 , wherein the at least one inert diluent is selected from calcium carbonate, calcium phosphate, lactose, and combinations thereof.

13. The method according to claim 10 , wherein the one or more excipients or carriers comprise at least one lubricant.

14. The method according to claim 13 , wherein the at least one lubricant is selected from the group consisting of magnesium stearate, talc, and combinations thereof.

15. The method according to claim 10 , wherein the one or more excipients or carriers comprise at least one distintegrant.

16. The method according to claim 15 , wherein the at least one disintegrant is selected from corn starch, alginic acid, and combinations thereof.

17. The method according to claim 10 , wherein the one or more excipients or carriers comprise at least one binder.

18. The method according to claim 17 , wherein the at least one binder is selected from starch, gelatin, and combinations thereof.

19. The method according to claim 10 , wherein the one or more excipients or carriers comprise at least one agent for delaying release.

20. The method according to claim 19 , wherein the at least one agent for delaying release is selected from carboxymethyl cellulose, cellulose acetate phthalate, polyvinyl acetate, and combinations thereof.

21. The method according to claim 6 , wherein the tablet further comprises one or more sweeteners, one or more flavor enhancers, preservatives, or a combination thereof.

22. The method according to claim 6 , wherein the tablet further comprises magnesium stearate, talc, and microcrystalline cellulose.

23. The method according to claim 22 , wherein the tablet further comprises one or both of lactose and sodium-carboxymethyl starch.

24. The method according to claim 10 , wherein the tablet comprises a compressed mixture of flibanserin and the one or more excipients or carriers.

25. The method according to claim 6 , wherein the tablet is uncoated.

Assignments (1)
SECURITY INTEREST Recorded Feb 25, 2021
From: SPROUT PHARMACEUTICALS, INC.
To: GOODRICH, BRAXTON; WHITEHEAD, ROBERT
Reel/Frame 055407/0810 →
Priority Claims (1)
EP 01125020 · Oct 20, 2001 · regional
Continuity (11)
Continuation 16125883 · Sep 10, 2018
Continuation 15694317 · Sep 1, 2017
Continuation 15270167 · Sep 20, 2016
Continuation 14640055 · Mar 6, 2015
Continuation 14269373 · May 5, 2014
Continuation 13920354 · Jun 18, 2013
Continuation 13551036 · Jul 17, 2012
Continuation 11524268 · Sep 21, 2006
Continuation 10272603 · Oct 16, 2002
Provisional Application 60348911 · Oct 23, 2001
Related Publication 20190262336A1 · Aug 29, 2019