High fat human milk products
The disclosure features a human milk cream composition as well as methods of making a human milk cream composition and using a human milk cream composition. In particular, the disclosure features a method of using a human milk cream composition to raise the caloric content of human milk.
1. A method for providing supplemental nutrition to a subject in need thereof comprising administering to the subject a standardized human milk cream composition comprising about 18% to about 30% human milk fat and about 2.0 kcal/mL to about 3.0 kcal/mL.
2. The method of claim 1 , wherein the subject in need thereof is an infant.
3. The method of claim 2 , wherein the infant is a preterm infant or a very low birthweight infant.
4. The method of claim 1 , wherein the standardized human milk cream composition is added to a volume of human milk and administered to the subject enterally.
5. The method of claim 4 , wherein the standardized human milk cream composition is added to a volume of human milk in an amount sufficient to raise the caloric content of the human milk.
6. The method of claim 5 , wherein the standardized human milk cream composition is added to a volume of human milk sufficient to raise the caloric content of the human milk to about 24 kcal/oz or about 26 kcal/oz.
7. The method of claim 1 , wherein the standardized human milk cream composition comprises about 25% human milk fat and about 2.5 kcal/mL.
8. The method of claim 1 , wherein the standardized human milk cream composition comprises human milk cream and water.
9. The method of claim 1 , wherein the standardized human milk cream composition comprises human milk cream and permeate.
10. The method of claim 1 , wherein the standardized human milk cream composition is produced from pooled human milk from qualified donors.
11. The method of claim 10 , wherein the pooled milk is screened for contaminants, pathogens and drugs.
12. The method of claim 1 , wherein the standardized human milk cream composition has been treated to reduce bioburden.
13. The method of claim 12 , wherein the standardized human milk cream composition has been pasteurized.
14. The method of claim 1 , wherein standardized human milk cream composition is provided to a subject in need thereof in an amount sufficient to increase at least one growth parameter.
15. The method of claim 14 , wherein the at least one growth parameter is length velocity, head circumference velocity, and/or weight velocity.