Medicament delivery devices with wireless connectivity and event detection
A computer-implemented method includes establishing a communications link, via a short-range wireless protocol, between a mobile computing device and a medicament delivery device. A user input selecting a motion profile of the medicament delivery device is then received in response to an input prompt. A wireless signal is received from the medicament delivery device, the wireless signal associated with an actual motion profile of the medicament delivery device. A notification is produced to indicate a motion difference between the actual motion profile and the target motion profile. In some embodiments, the method optionally includes modifying the target motion profile based on the motion profile over a time period of at least one week, the notification indicating a motion difference between the motion profile and the modified target motion profile.
1. An apparatus, comprising:
a medicament delivery device including an actuator configured to initiate delivery of a medicament; and
an electronic circuit system coupled to at least one of a housing of the medicament delivery device or a cover configured to receive a portion of the medicament delivery device, the electronic circuit system including:
a first sensor configured to produce a motion signal associated with at least one of a position, a velocity, an acceleration, or an orientation of at least one of the housing or the cover;
a second sensor configured to produce an actuation signal in response to movement of the actuator;
a motion module implemented in at least one of a memory or a processing device, the motion module configured to receive the motion signal and determine, based on the motion signal, a motion profile associated with the medicament delivery device; and
a radio configured to electronically communicate with a computing device via a short-range wireless communication protocol, the radio configured to send a first wireless signal to establish a communications link between the computing device and the medicament delivery device, the radio configured to send a second wireless signal associated with the motion profile of the medicament delivery device, the radio configured to send a third wireless signal associated with actuation of the medicament delivery device.
2. The apparatus of claim 1 , wherein the medicament delivery device is any one of an auto-injector, a pen injector, a medication pump, a prefilled syringe, a nasal delivery device or an inhaler.
3. The apparatus of claim 1 , wherein the first sensor is an accelerometer that detects at least one of the position, the velocity, the acceleration, or the orientation of at least one of the housing or the cover.
4. The apparatus of claim 1 , wherein the electronic circuit system further includes:
a predictive module implemented in at least one of the memory or the processing device, the predictive module configured to determine a target motion profile based on the motion profile received over a time period; and
a notification module implemented in at least one of the memory or the processing device, the notification module configured to produce a notification signal indicating a motion difference between the motion profile and the target motion profile,
the radio configured to send a third wireless signal associated with the notification signal.
5. The apparatus of claim 4 , wherein:
the motion profile is a daily motion profile; and
the time period is at least a month.
6. The apparatus of claim 1 , wherein the memory is configured to store an actuation profile of the medicament delivery device, the actuation profile including the actuation signal and a time stamp associated with the actuation signal.
7. The apparatus of claim 1 , wherein the second sensor is a switch configured to move between a first state and a second state.
8. The apparatus of claim 1 , wherein the electronic circuit system includes a removal sensor configured to produce a removal signal in response to removal of the portion of the medicament delivery device from the cover,
the radio configured to send a fourth wireless signal associated with removal of the portion of the medicament delivery device from the cover.
9. The apparatus of claim 1 , wherein:
the first sensor is an accelerometer configured to detect at least one of the position, the velocity, the acceleration, or the orientation of at least one of the housing or the cover at a first sample rate;
the electronic circuit system includes a removal sensor configured to produce a removal signal in response to removal of a portion of the medicament delivery device from the cover; and
the accelerometer is configured to receive the at least one of the position, the velocity, the acceleration, or the orientation of at least one of the housing or the cover at a second sample rate, the second sample rate greater than the first sample rate.
10. The apparatus of claim 8 , wherein:
the memory of the electronic circuit system is configured to store a cover removal profile, the cover removal profile including the removal signal and a time stamp associated with the removal signal.
11. The apparatus of claim 8 , wherein the removal sensor is a switch configured to move between a first state and a second state.
12. An apparatus, comprising:
a medicament delivery device; and
an electronic circuit system coupled to at least one of a housing of the medicament delivery device or a cover configured to receive a portion of the medicament delivery device, the electronic circuit system including:
a sensor configured to produce a motion signal associated with at least one of a position, a velocity, an acceleration, or an orientation of at least one of the housing or the cover;
a motion module implemented in at least one of a memory or a processing device, the motion module configured to receive the motion signal and determine, based on the motion signal, a motion profile associated with the medicament delivery device;
a notification module implemented in at least one of the memory or the processing device, the notification module configured to produce a first notification signal indicating a motion profile difference between the motion profile and a first target motion profile stored in the memory; and
a predictive module implemented in at least one of the memory or the processing device, the predictive module configured to determine a second target motion profile based on the motion profile received over a first time period,
the notification module configured to produce a second notification signal indicating a motion profile difference between the motion profile and the second target motion profile.
13. The apparatus of claim 12 , wherein:
the predictive module is configured to determine the first target motion profile.
14. The apparatus of claim 12 , further comprising:
a radio configured to electronically communicate with a computing device via a short-range wireless communication protocol, the radio configured to send a first wireless signal to establish a communications link between the computing device and the medicament delivery device, the radio configured to send a second wireless signal associated with the motion profile of the medicament delivery device.
15. The apparatus of claim 14 , wherein:
the radio is configured to send a third wireless signal associated with the first notification signal.
16. The apparatus of claim 15 , wherein:
the radio is configured to send a fourth wireless signal associated with the second notification signal.
17. The apparatus of claim 12 , wherein:
the motion profile is a daily motion profile; and
the time period is at least a month.
18. An apparatus, comprising:
a medicament delivery device; and
an electronic circuit system coupled to at least one of a housing of the medicament delivery device or a cover configured to receive a portion of the medicament delivery device, the electronic circuit system including:
an accelerometer configured to detect at least one of a position, a velocity, an acceleration, or an orientation of at least one of the housing or the cover at a first sample rate and a second sample, the second sample rate being greater than the first sample rate;
a motion module implemented in at least one of a memory or a processing device, the motion module configured to receive a motion signal and determine, based on the motion signal, a motion profile associated with the medicament delivery device;
a radio configured to electronically communicate with a computing device via a short-range wireless communication protocol, the radio configured to send a first wireless signal to establish a communications link between the computing device and the medicament delivery device, the radio configured to send a second wireless signal associated with the motion profile of the medicament delivery device; and
a removal sensor configured to produce a removal signal in response to removal of a portion of the medicament delivery device from the cover.