Immunomodulatory pharmaceutical compositions
The invention provides immunomodulatory pharmaceutical compositions that include a synthetic peptide and one or more immune tolerance enhancers.
1. A pharmaceutical composition, comprising
a synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2); and
rapamycin.
2. A pharmaceutical composition, comprising
a synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2); and
fingolimod (FTY720).
3. A pharmaceutical composition, comprising
a synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2); and
a sphingosine kinase 1 inhibitor.
4. The pharmaceutical composition of claim 1 , consisting essentially of:
a synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2); and
rapamycin.
5. The pharmaceutical composition of claim 2 , consisting essentially of:
a synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2); and
fingolimod (FTY720).
6. The pharmaceutical composition of claim 3 , consisting essentially of:
a synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2); and
a sphingosine kinase 1 inhibitor.