Optimized intrathecal drug delivery

1. An intrathecal drug delivery system configured to monitor one or more physiological conditions of a patient to look for opportunities to time medicament delivery to coincide with patient activity inferring heightened cerebrospinal fluid oscillations, thereby improving dispersion of the medicament within an intrathecal space of the patient, the intrathecal drug delivery system comprising:

an implantable medical pump configured to deliver medicament within the intrathecal space of a patient;

one or more physiological sensors configured to monitor at least one of a heart rate, respiratory rate, oxygen saturation, or perspiration rate of the patient; and

an external programmer configured to program the implantable medical pump with a treatment protocol specifying at least one period of time during which a specified quantity of medicament is to be administered,

wherein during the at least one period of time, the implantable medical pump is configured to administer the specified quantity of medicament upon at least one of the monitored heart rate, respiratory rate, oxygen saturation, or perspiration rate meeting or exceeding a patient specific active state threshold.

2. The intrathecal drug delivery system of claim 1 , wherein at least one of the one or more physiological sensors further comprise an orientation sensor, motion sensor, or accelerometer.

3. The intrathecal drug delivery system of claim 1 , wherein at least one of the one or more physiological sensors is at least one of incorporated into the implantable medical pump or worn by the patient.

4. The intrathecal drug delivery system of claim 1 , wherein at least one of the one or more physiological sensors wirelessly communicates with the implantable medical pump.

5. The intrathecal drug delivery system of claim 1 , wherein at least one of the one or more physiological sensors continuously monitors a physiological condition of the patient.

6. The intrathecal drug delivery system of claim 1 , wherein data from at least one of the one or more physiological sensors is used to establish the patient specific active state threshold.

7. The intrathecal drug delivery system of claim 6 , wherein the patient specific active state threshold is utilized as a trigger for the delivery of medicament.

8. The intrathecal drug delivery system of claim 1 , wherein the at least one period of time is defined to begin at a specified time of day and extend for a defined duration.

9. The intrathecal drug delivery system of claim 1 , wherein the intrathecal drug delivery system is further configured to provide a notification to suggest at least one of modifying patient posture to the desired posture or increasing patient activity.

10. A method of timing intrathecal drug delivery to correspond with heightened cerebrospinal fluid oscillations, the method comprising:

programming an implantable medical pump with a treatment protocol specifying at least one period of time during which a specified quantity of medicament is to be delivered into the intrathecal space of patient;

monitoring one or more physiological conditions of the patient with one or more physiological sensors to determine at least one of a heart rate, respiratory rate, oxygen saturation, or perspiration rate; and

timing the delivery of the medicament to coincide with at least one of the monitored heart rate, respiratory rate, oxygen saturation, or perspiration rate meeting or exceeding a patient specific active state threshold, thereby improving dispersion of the medicament within the intrathecal space of the patient.

11. The method of claim 10 , further comprising monitoring a posture of the patient.

12. The method of claim 10 , wherein at least one of the one or more physiological sensors continuously monitors a physiological condition of the patient.

13. The method of claim 12 , further comprising receiving and storing data from at least one of the one or more physiological sensors on at least one of a server or external programmer.

14. The method of claim 13 , further comprising utilizing the stored data from at least one of the one or more physiological sensors to establish the patient specific active state threshold.

15. The method of claim 14 , wherein the patient specific active state threshold is utilized as a trigger for the delivery of medicament.