IP Library Granted Patent US 11,123,136
Granted Patent B2
US 11,123,136 · App. 16/444,831 · Granted Sep 21, 2021

Applicator and tissue interface module for dermatological device

Inventors: Yoav Ben-Haim (San Francisco, CA); Peter J. Bentley (San Jose, CA); Donghoon Chun (Sunnyvale, CA); Daniel Francis (Mountain View, CA); Jessi E. Johnson (Sunnyvale, CA); Kevin Shan (Pasadena, CA); Ted Y. Su (Sunnyvale, CA); Steven W. Kim (Los Altos, CA)
Assignee: MIRADRY, INC.
A61B18/1815A61N5/04A61B2017/00681A61B2018/00023A61B2018/00291A61B2018/00452A61B2018/00821
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Quick Facts
Patent No.
US 11,123,136
App. No.
16/444,831
Granted
Sep 21, 2021
Kind
B2
Abstract

A tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Claims (25)

1. A device for treating a patient comprising:

a tissue interface module coupled to an applicator, wherein a distal end of the applicator is positioned in an applicator chamber of the tissue interface module, the tissue interface module further having a tissue acquisition chamber separated from the applicator chamber via a flexible bio-barrier;

a vacuum path extending from a distal end of the tissue acquisition chamber to a proximal end of the applicator chamber, the vacuum path being adapted to facilitate the flow of air from the tissue acquisition chamber to the applicator chamber when the applicator chamber is attached to a vacuum source;

wherein the vacuum path is adapted to facilitate creation of a vacuum in the tissue acquisition chamber to thereby facilitate treatment of a patient.

2. The device of claim 1 , wherein the bio-barrier is positioned between, and in fluid communication with, the applicator chamber and the tissue acquisition chamber and is substantially impermeable to air or fluids.

3. The device of claim 1 , wherein the bio-barrier is microwave transparent.

4. The device of claim 1 , wherein the vacuum path further comprises a filter, a vacuum trap and an expandable aperture.

5. The device of claim 1 , wherein the vacuum path is adapted to facilitate creation of the vacuum to facilitate pulling of a patient's skin into the tissue acquisition chamber.

6. The device of claim 1 , wherein an attachment mechanism is positioned in the applicator chamber and is adapted to attach the tissue interface module to the applicator.

7. The device of claim 6 , further comprising a sealing member positioned at a proximal side of the applicator chamber.

8. The device of claim 1 , wherein the vacuum path further comprises a filter and a variable flow restrictor, the variable flow restrictor being positioned between, and in communication with, the tissue acquisition chamber and the filter.

9. The device of claim 8 , wherein the variable flow restrictor comprises a flexible element adapted to expand a flow opening in the vacuum path in response to a pressure difference between the tissue acquisition chamber and the filter.

10. The device of claim 6 , wherein the attachment mechanism comprises at least one attachment plate positioned in the applicator chamber, the attachment plate adapted to magnetically attach to elements of a magnetic circuit positioned on a distal end of the applicator.

11. The device of claim 10 , wherein the attachment plate comprises a magnetic element adapted to form a magnetic circuit with magnetic elements in the applicator.

12. The device of claim 11 , wherein the attachment plate comprises a ferromagnetic plate.

13. A device for treating a patient comprising:

a tissue interface module coupled to an applicator, wherein a distal end of the applicator is positioned in an applicator chamber of the tissue interface module, the tissue interface module further having a tissue acquisition chamber separated from the applicator chamber via a flexible bio-barrier;

a vacuum path extending from a distal end of the tissue acquisition chamber to a proximal end of the applicator chamber, the vacuum path being adapted to facilitate the flow of air from the tissue acquisition chamber to the applicator chamber when the applicator chamber is attached to a vacuum source; and

a filter disposed in the vacuum path connecting the applicator chamber and the tissue acquisition chamber, the filter being permeable to air and substantially impermeable to liquids;

wherein the vacuum path is adapted to facilitate creation of a vacuum in the tissue acquisition chamber to thereby facilitate treatment of a patient.

14. The device of claim 13 , wherein the bio-barrier is positioned between, and in fluid communication with, the applicator chamber and the tissue acquisition chamber and is substantially impermeable to air or fluids.

15. The device of claim 13 , wherein the bio-barrier is microwave transparent.

16. The device of claim 13 , wherein the vacuum path further comprises a variable flow restrictor, the variable flow restrictor being positioned between, and in communication with, the tissue acquisition chamber and the filter.

17. The device of claim 16 , wherein the variable flow restrictor comprises a flexible element adapted to expand a flow opening in the vacuum path in response to a pressure difference between the tissue acquisition chamber and the filter.

18. The device of claim 13 , wherein the vacuum path is adapted to facilitate creation of the vacuum to facilitate pulling of a patient's skin into the tissue acquisition chamber.

Assignments (9)
SECURITY INTEREST Recorded Oct 1, 2024
From: MIRADRY, INC.
To: WESTERN ALLIANCE BANK
Reel/Frame 068752/0533 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FINANCIAL TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0573 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FUNDING IV TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0486 →
RELEASE OF SECURITY INTEREST (REVOLVING) Recorded Jun 22, 2021
From: MIDCAP FUNDING IV TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0001 →
RELEASE OF SECURITY INTEREST (TERM) Recorded Jun 22, 2021
From: MIDCAP FINANCIAL TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0044 →
SECURITY INTEREST SUPPLEMENT (REVOLVING) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FUNDING IV TRUST, AS AGENT
Reel/Frame 055379/0016 →
REAFFIRMATION AGREEMENT AND AMENDMENT TO SECURITY AGREEMENT (TERM) Recorded Feb 23, 2021
From: SIENTRA, INC.; MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 055436/0001 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049650/0001 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049649/0450 →
Continuity (7)
Continuation 15090273 · Apr 4, 2016
Division 13563656 · Jul 31, 2012
Provisional Application 61513834 · Aug 1, 2011
Provisional Application 61555410 · Nov 3, 2011
Provisional Application 61673697 · Jul 19, 2012
Provisional Application 61676833 · Jul 27, 2012
Related Publication 20200100837A1 · Apr 2, 2020