ELECTRONIC DEVICES AND METHODS FOR TREATMENT UTILIZING ANTIPSYCHOTICS IN COMBINATION WITH DIGITAL THERAPIES

1 . A method for the treatment of schizophrenia, in a subject, in need thereof, comprising administering to said subject an effective amount of an antipsychotic, wherein

i) the antipsychotic is provided in combination with a computer-implemented mobile device; and

ii) the computer-implemented mobile device comprises:

a display;

an input device;

one or more processors; and

memory storing one or more programs configured to be executed by the one or more processors, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

2 . A method for the treatment of positive symptoms of schizophrenia, in a subject, in need thereof, comprising administering to said subject an effective amount of an antipsychotic, wherein,

i) the antipsychotic is provided in combination with a computer-implemented mobile device; and

ii) the computer-implemented mobile device comprises:

a display;

an input device;

one or more processors; and

memory storing one or more programs configured to be executed by the one or more processors, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

3 . A method for the treatment of negative symptoms of schizophrenia, in a subject, in need thereof, comprising administering to said subject an effective amount of an antipsychotic, wherein,

i) the antipsychotic is provided in combination with a computer-implemented mobile device; and

ii) the computer-implemented mobile device comprises:

a display;

an input device;

one or more processors; and

memory storing one or more programs configured to be executed by the one or more processors, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

4 . A method for treatment of depression associated with schizophrenia, in a subject, in need thereof, comprising administering to said subject an effective amount of an antipsychotic, wherein,

i) the antipsychotic is provided in combination with a computer-implemented mobile device; and

ii) the computer-implemented mobile device comprises:

a display;

an input device;

one or more processors; and

memory storing one or more programs configured to be executed by the one or more processors, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

5 . A method for treatment of insomnia associated with schizophrenia, in a subject, in need thereof, comprising administering to said subject an effective amount of an antipsychotic, wherein,

i) the antipsychotic is provided in combination with a computer-implemented mobile device; and

ii) the computer-implemented mobile device comprises:

a display;

an input device;

one or more processors; and

memory storing one or more programs configured to be executed by the one or more processors, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

6 . The method according to any one of claims 1 to 5 , wherein the computer-implemented mobile device delivers behavioral therapy that focuses on symptoms of psychosis, mood management, sleep hygiene, medication adherence or social skills.

7 . The method according to claim 6 , wherein the behavioral therapy is cognitive behavioral therapy for schizophrenia, that focuses on one or more: i) symptoms of psychosis, ii) mood management, iii) sleep hygiene, iv) medication adherence and v) social skills.

8 . A method for the treatment of schizophrenia, in a subject, in need thereof, comprising administering to said subject an effective amount of an antipsychotic, wherein

i) the antipsychotic is provided in combination with a digital-therapeutic; and

ii) the digital-therapeutic delivers behavioral therapy.

9 . The method according to claim 8 , wherein the digital-therapeutic is implemented via a mobile device selected from the group comprising a smartphone, a laptop computer, a tablet computer, and a wearable computer.

10 . A method for the treatment of schizophrenia, in a subject, in need thereof, comprising administering to said subject an effective amount of an antipsychotic, wherein the method is combined with computer-implemented behavioral therapy.

11 . The method according to claim 10 , wherein the computer-implemented behavioral therapy is provided by a computerized device selected from the group comprising a smartphone, a laptop computer, a tablet computer, and a wearable computer.

12 . A combination comprising an antipsychotic and a computer-implemented mobile device;

wherein the computer-implemented mobile device comprises:

a display;

an input device;

one or more processors; and

memory storing one or more programs configured to be executed by the one or more processors, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

13 . A combination comprising an antipsychotic and a digital-therapeutic, wherein the digital-therapeutic delivers behavioral therapy.

14 . A computerized method for targeted delivery of digital therapies, the method comprising:

at an electronic device including a display and an input device:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

15 . A non-transitory computer-readable storage medium storing one or more programs configured to be executed by one or more processors of an electronic device with a display and an input device, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.

16 . An electronic device, comprising:

a display;

an input device;

one or more processors; and

memory storing one or more programs configured to be executed by the one or more processors, the one or more programs including instructions for:

displaying, on the display, a query interface, the query interface presenting a plurality of queries, including a first query;

while displaying the query interface, receiving, via the input device, a first sequence of inputs;

in response to receiving the first sequence of inputs, displaying a response summary interface, the response summary interface including:

in accordance with the response to the first query being a response of a first type, displaying, in a first region of the response summary interface, a first response element corresponding to the first query, the first response element including at least a first selectable graphical element corresponding to a first set of digital therapies associated with the first query; and

in accordance with the response to the first query being a response of a second type, different than the first type, displaying, in a second region of the response summary interface, a second response element, wherein the second response element corresponds to the first query and does not include the first selectable graphical element corresponding to the first set of digital therapies associated with the first query.