IP Library › Granted Patent US 10,604,760
Granted Patent B2
US 10,604,760 · App. 16/450,324 · Granted Mar 31, 2020

Combination comprising immunostimulatory oligonucleotides

Inventors: Matthias Schroff (Berlin, DE); Manuel Schmidt (Berlin, DE); Kerstin Kapp (Berlin, DE); Alfredo Zurlo (Berlin, DE)
Assignee: Mologen AG
C12N15/117A61K31/7088A61K39/3955A61K39/39541A61P35/00C07K16/2818C07K16/2827C07K16/30C12N15/111A61K2039/505C12N2310/17C12N2310/32C12N2310/344C12N2310/531C12N2310/532C12N2320/31
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Quick Facts
Patent No.
US 10,604,760
App. No.
16/450,324
Granted
Mar 31, 2020
Kind
B2
Abstract

The invention relates to a combination and its use for the treatment of diseases. The instant disclosure provides a combination of a so-called T-cell regulator selected from the group comprising PD1, PD-L1, OX40, TIM-3, LAGS, CD137(4-1BB) and a non-codiung immuno-modulating DNA.

Claims (1)

1. A linear open-chained non-coding sequence of deoxyribonucleic acids selected from SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9 and SEQ ID NO: 11.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2021
From: SCHROFF, MATTHIAS; SCHMIDT, MANUEL; KAPP, KERSTIN; ZURLO, ALFREDO
To: MOLOGEN AG
Reel/Frame 057451/0441 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 28, 2020
From: MOLOGEN AG
To: GILEAD SCIENCES, INC.
Reel/Frame 054858/0419 →