Peripheral antegrade perfusion and occlusion device

1. An aortic occlusion and perfusion device, comprising:

an expandable member configured to expand within the aorta to secure the device within the aorta, the expandable member comprising one or more porous regions configured to perfuse at least one of the brachiocephalic artery, the left common carotid artery, or the left subclavian artery when blood is supplied to the expandable member;

a catheter extending proximally from the expandable member and in fluid communication with the expandable member, the catheter defining openings along its length through which blood can pass with one or more of the openings located proximal to the expandable member and one or more of the openings located within the expandable member, the catheter defining a lumen in fluid communication with the one or more openings located within the expandable member and with the one or more openings located proximal to the expandable member; and

a flow control sheath disposed around the catheter proximal to the expandable member such that axial movement of the flow control sheath relative to the catheter selectively occludes or uncovers the one or more openings located proximal to the expandable member.

2. The aortic occlusion and perfusion device of claim 1 , wherein the lumen of the catheter terminates at a terminus such that the lumen is not in fluid communication with a distal end portion of the catheter.

3. The aortic occlusion and perfusion device of claim 2 , wherein the terminus is proximal to the distal end portion of the catheter.

4. The aortic occlusion and perfusion device of claim 2 , wherein the terminus is located in the portion of the catheter disposed within the expandable member.

5. The aortic occlusion and perfusion device of claim 2 , wherein the terminus comprises a wall inside the lumen of the catheter.

6. The aortic occlusion and perfusion device of claim 1 , wherein:

the lumen of the catheter is a first lumen; and

the catheter further defines a second lumen configured to be in fluid communication with the ascending aorta.

7. The aortic occlusion and perfusion device of claim 1 , wherein a distal end portion of the expandable member is configured to expand to a greater diameter than a proximal end portion of the expandable member.

8. The aortic occlusion and perfusion device of claim 7 , wherein the expandable member comprises an elastomeric material; and

a thickness of the elastomeric material at the proximal end portion is greater than a thickness of the elastomeric material at the distal end portion such that the distal end portion is configured to expand to a greater diameter than the proximal end portion for a given pressure within the expandable member.

9. The aortic occlusion and perfusion device of claim 1 , wherein the one or more porous regions comprise a plurality of openings or valves configured to open when the pressure inside the expandable member reaches a predetermined pressure.

10. The aortic occlusion and prefusion device of claim 1 , wherein the one or more porous regions of the expandable member comprise three discrete porous regions spaced apart axially by non-porous regions, each of the three discrete porous regions being configured to be located adjacent the ostia of at least one of the brachiocephalic artery, the left common carotid artery, or the left subclavian artery.

11. The aortic occlusion and perfusion device of claim 1 , wherein the flow control sheath is configured to control pressure in the expandable member and blood flow out of the expandable member by selectively occluding or uncovering the one or more openings located proximal to the expandable member.

12. The aortic occlusion and perfusion device of claim 1 , wherein the catheter is configured to be placed in fluid communication with the descending aorta via the one or more openings located proximally of the expandable member for perfusing blood to a lower portion of a patient's body.

13. An aortic occlusion and perfusion device, comprising:

an expandable member configured to expand within the aorta to secure the device within the aorta;

a catheter extending proximally from the expandable member and in fluid communication with the expandable member, the catheter defining openings along its length through which blood can pass with one or more of the openings located proximal to the expandable member and one or more of the openings located within the expandable member, the catheter defining a lumen in fluid communication with the one or more openings located within the expandable member and with the one or more openings located proximal to the expandable member, the lumen terminating at a terminus such that the lumen is not in fluid communication with a distal end portion of the catheter; and

a flow control sheath disposed around the catheter proximal to the expandable member such that axial movement of the flow control sheath relative to the catheter selectively occludes or uncovers the one or more openings located proximal to the expandable member.

14. The aortic occlusion and perfusion device of claim 13 , wherein the terminus is proximal to the distal end portion of the catheter.

15. The aortic occlusion and perfusion device of claim 13 , wherein the terminus is located in the portion of the catheter disposed within the expandable member.

16. The aortic occlusion and perfusion device of claim 13 , wherein the terminus comprises a wall inside the lumen of the catheter.

17. The aortic occlusion and perfusion device of claim 13 , wherein:

the lumen of the catheter is a first lumen; and

the catheter defines a second lumen configured to be in fluid communication with the ascending aorta.

18. An aortic occlusion and perfusion device, comprising:

an expandable member configured to expand within the aorta to secure the device within the aorta;

a catheter extending proximally from the expandable member and in fluid communication with the expandable member, the catheter defining openings along its length through which blood can pass with one or more of the openings located proximal to the expandable member and one or more of the openings located within the expandable member; and

wherein the expandable member comprises three discrete porous regions spaced apart axially by non-porous regions, each of the porous regions being configured to be located adjacent the ostia of at least one of the brachiocephalic artery, the left common carotid artery, or the left subclavian artery.

19. The aortic occlusion and perfusion device of claim 18 , wherein the porous regions extend around a circumference of the expandable member.

20. The aortic occlusion and perfusion device of claim 18 , wherein the porous regions comprise a plurality of openings or valves configured to open when the pressure inside the expandable member reaches a predetermined pressure.