BASIC CORE MATERIAL ENCAPSULATED IN AN INORGANIC SHELL SUITABLE FOR USE IN BIOLOGICAL CARRIER MATERIALS
A (e.g. hardenable dental) composition is described comprising (e.g. a first part comprising) an encapsulated material wherein the encapsulated material comprises a basic core material and an inorganic shell material comprising a metal oxide surrounding the core; and (e.g. a second part comprising) water or an acidic component. Also described is an encapsulated material (e.g. suitable for use in a biological carrier material) comprising a basic core material and an inorganic shell material comprising a metal oxide surrounding the core.
1 . A dental composition comprising:
a first part comprising an encapsulated material wherein the encapsulated material comprises a basic pH core material and an inorganic shell material comprising a metal oxide surrounding the core; wherein the basic core material, the inorganic shell material, or the combination thereof, is hardenable; and
a second part comprising water or an acidic component.
2 . (canceled)
3 . The dental composition of claim 1 , wherein the shell is degradable by the second part.
4 . (canceled)
5 . The dental composition of claim 1 , wherein the basic core material comprises a component having a pKa ranging from 8-14.
6 . (canceled)
7 . The dental composition of claim 1 , wherein the basic core material comprises a material that releases calcium ions.
8 . (canceled)
9 . The dental composition of claim 1 , wherein the shell is a continuous film having a thickness less than 500 nm.
10 . (canceled)
11 . The dental composition of claim 1 , wherein the inorganic shell material comprises a metal oxide having a pKa of 6-8.
12 - 14 . (canceled)
15 . The dental composition of claim 1 , wherein the basic core material comprises calcium silicate.
16 . The dental composition of claim 1 , wherein the basic core material is a dental filler comprising neutral metal oxide(s) that have low solubility in the second part.
17 . The dental composition of claim 1 , wherein the dental composition comprises a material that promotes remineralization by release of calcium ions, phosphorus ion, fluorine ions, or a combination thereof.
18 . The dental composition of claim 16 , wherein the composition further comprises at least one second filler.
19 . The dental composition of claim 18 , wherein the second filler comprises nanoscopic particulate filler.
20 . The dental composition of claim 19 , wherein the second filler comprises zirconia, silica, or mixture thereof.
21 . The dental composition of claim 20 , wherein the second filler comprise a nanocluster filler.
22 . The dental composition of claim 1 , wherein the first and/or second part comprises a polymerizable material.
23 . The dental composition of claim 22 , wherein the polymerizable material comprises a hydroxy functional (meth)acrylate monomer, an acidic polymer, or a combination thereof.
24 - 27 . (canceled)
28 . A composition comprising:
an encapsulated material wherein the encapsulated material comprises a basic pH core material and an inorganic shell material comprising a metal oxide surrounding the core, wherein the basic core material, the inorganic shell material, or the combination thereof, is hardenable; and
water or an acidic component.
29 . (canceled)
30 . The composition of claim 28 , wherein the encapsulated material is suitable for use in a biological carrier material comprising a basic core material and an inorganic shell material.
31 - 39 . (canceled)
40 . A method of promoting remineralization comprising:
providing the composition according to claim 1 , wherein the basic core further comprises a material that promotes remineralization by the release calcium ions, phosphorous containing ions, fluoride ions, or a combination thereof; and
applying the composition to a tooth or bone structure.
41 . (canceled)
42 . A method of increasing the average alkaline phosphatase (ALP) activity of tooth pulp cells comprising
providing the composition according to claim 1 , wherein the basic core further comprises a material that promotes remineralization; and
applying the composition to a tooth or bone structure.
43 . A composition according to claim 1 for use for applying to a tooth or bone structure wherein the composition
provides a delayed release of a basic pH core material;
provides a delayed increase in basicity;
promotes remineralization of a tooth or bone structure by the release calcium ions, phosphorous containing ions, fluoride ions, or a combination thereof;
increases the average alkaline phosphatase (ALP) activity of pulp cells;
or a combination thereof.
44 - 51 . (canceled)
52 . A method of making an encapsulated material comprising:
providing a basic pH core material, wherein the basic core material comprises calcium; and
encapsulating the basic core material with an inorganic shell material comprising a metal oxide by means of at least one vapor deposition technique, wherein the basic core material, the inorganic shell material, or the combination thereof, is hardenable.
53 - 55 . (canceled)