Multiple modality body composition analysis
Systems and methods for determining body composition by combining dual-energy x-ray (DXA) technology with three-dimensional (3D) optical technology and/or bioimpedance technology. A multi-modality scanning system may include a dual-energy x-ray source and an x-ray detector mounted to opposing sides a c-arm and configured to scan a patient on a optically translucent table. The system may also include one or more 3D optical imaging devices to capture 3D optical images of the patient substantially concurrently with the emission of the dual energy x-rays. A bioimpedance machine may also be included in the multi-modality scanning system. Data based on the dual-energy x-rays may be combined with the data from the 3D optical images and/or the bioimpedance data to generate values of at least three compartments selected from: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
1. A system comprising:
a support structure configured to move along an axis of a scanning target;
a dual-energy x-ray source mounted to the support structure, the dual energy x-ray source configured to emit dual-energy x-rays towards the scanning target along a scan path;
an x-ray detector configured to detect the dual-energy x-rays emitted from the dual-energy x-ray source after passing through the scanning target;
a first 3D optical imaging device mounted to the support structure and configured to obtain a first 3D optical image of a first side of the scanning target along the scan path; and
a second 3D optical imaging device mounted to the support structure and configured to concurrently obtain a second 3D optical image of a second side of the scanning target, the second side being opposite the first side with respect to the scanning target; and
a processing device communicatively coupled to the x-ray detector and the first 3D optical imaging device;
wherein at least the first 3D optical imaging device and the second 3D optical imaging device are fixed in place with respect to the scanning target to capture surfaces of the scanning target to form a 3D model of the scanning target; and
the processing device is configured to determine, on a per-pixel basis, amounts of at least three of: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
2. The system of claim 1 , further comprising an optically translucent patient support table or wall on which the scanning target is positioned, wherein the optically translucent table is disposed between the dual energy x-ray source and the detector.
3. The system of claim 1 , further comprising a scale to measure the weight of the scanning target.
4. The system of claim 3 , wherein the x-ray source is configured to move along the support structure in a direction transverse to the longitudinal axis of the scanning target.
5. The system of claim 1 , wherein:
the support structure has a first arm and a second arm, the first arm and the second arm disposed on opposite sides of a scanning target; and
the first 3D optical imaging device is mounted to the first arm.
6. The system of claim 1 , wherein the first 3D optical imaging device is selected from a group consisting of a stereoscopic device, a laser scanning device, a structured light device, and a modulated light device.
7. The system of claim 1 , wherein the processing device is configured to compute a thickness of the scanning target on a per pixel basis.
8. The system of claim 1 , further comprising a bioimpedance analysis device mounted to a portion of the system and communicatively coupled to the processing device.
9. The system of claim 1 , wherein the system is configured to scan a patient in a standing position.
10. A system comprising:
a dual-energy x-ray source configured to move vertically along a longitudinal axis of the scanning target, the dual energy x-ray source configured to emit dual-energy x-rays towards a first side of the scanning target;
an x-ray detector configured to move in a vertical scan path along the longitudinal axis of the scanning target and configured to detect the dual-energy x-rays emitted from the dual-energy x-ray source after passing through the scanning target;
a first 3D optical imaging device configured to obtain a first 3D optical image of the first side of the scanning target along the vertical scan path;
a second 3D optical imaging device configured to concurrently obtain a second 3D optical image of a second side of the scanning target along the vertical scan path, the second side being opposite the first side with respect to the scanning target; and
a processing device communicatively coupled to the x-ray detector and the first 3D optical imaging device;
wherein at least the first 3D optical imaging device and the second 3D optical imaging device are fixed in place with respect to the scanning target to capture surfaces of the scanning target to form a 3D model of the scanning target; and
the processing device is configured to determine, on a per-pixel basis, amounts of at least three of: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
11. The system of claim 10 , further comprising a radiolucent, transparent wall disposed between the dual-energy x-ray source and the x-ray detector.
12. The system of claim 1 , wherein the first 3D optical imaging device is configured to capture the 3D optical image within one second before or after the dual-energy x-rays are emitted towards the scanning target.
13. The system of claim 10 , wherein the first 3D optical imaging device is configured to capture the optical image within one second before or after the dual-energy x-rays are emitted towards the scanning target.
14. The system of claim 1 , wherein the first 3D optical imaging device is configured to capture a position and shape of a patient at the same time as information from the dual-energy x-rays is obtained.
15. The system of claim 10 , wherein at least one of the first 3D optical imaging device and the second 3D optical imaging device is configured to capture a position and shape of a patient at the same time as information from the dual-energy x-rays is obtained.
16. A system comprising:
a support structure configured to move along an axis of a scanning target;
a dual-energy x-ray source mounted to the support structure, the dual energy x-ray source configured to emit dual-energy x-rays towards the scanning target along a scan path;
an x-ray detector configured to detect the dual-energy x-rays emitted from the dual-energy x-ray source after passing through the scanning target; and
at least one optical imaging device mounted to the support structure and configured to obtain an optical image of a first side of the scanning target along the scan path;
a bioimpedance analysis device mounted to a portion of the system and communicatively coupled to a processing device, wherein a position of electrodes of the bioimpedance analysis device is based on at least one of dual-energy x-ray data provided by the dual-energy x-ray source and optical data provided by the at least one optical imaging device; and
the processing device being communicatively coupled to the x-ray detector and the at least one optical imaging device and being configured to determine, on a per-pixel basis, amounts of at least three of: bone, fat tissue, lean tissue, dehydrated lean tissue, and water.
17. The system of claim 1 , further comprising:
a third 3D optical imaging device mounted to the support structure and configured to obtain a third 3D optical image of the scanning target along the scan path;
wherein the third 3D optical image combined with the first 3D optical image and the second 3D optical image form the 3D model of the scanning target.
18. The system of claim 10 , further comprising:
a third 3D optical imaging device mounted to the support structure and configured to obtain a third 3D optical image of the scanning target along the scan path;
wherein the third 3D optical image combined with the first 3D optical image and the second 3D optical image form the 3D model of the scanning target.