Patent Application

App. No. 16/514,328

Abstract

Claims (23)

1 . A rupture-stable gelatin filled capsule, comprising xylose cross-linked gel masses wherein the xylose cross-linked masses are comprised of 0.01%-2% xylose solutions and gelatin masses, and wherein the xylose solutions and gelatin masses are mixed at temperatures from 135-200° F. and yield viscosities from 10,000-16,000 cps.

2 . The rupture-stable gelatin filled capsule as in claim 1 , comprised of 075%-1.25% xylose solutions.

3 . The rupture-stable gelatin filled capsule of claim 1 , wherein the mixing temperature is within 150-200° F.

4 . The rupture-stable gelatin filled capsule of claim 1 , wherein the xylose solution is prepared from xylose sugars, such as D-xylose, L-xylose, or DL-xylose.

5 . The rupture-stable gelatin filled capsule of claim 1 , wherein the gelatin masses comprise 8%-27% glycerin, 21-66% gelatin, and 17-53% water.

6 . The rupture-stable gelatin filled capsule of claim 1 , wherein the gelatin masses comprise 17.5% glycerin, 43.5% gelatin, and 35% water.

7 . The rupture-stable gelatin filled capsule of claim 1 , wherein the gelatin masses are of bovine, pork, fish, chicken, duck, or other poultry origin.

8 . The rupture-stable gelatin filled capsule of claim 1 , wherein the capsule contains nutraceutical ingredients.

9 . The rupture-stable gelatin filled capsule of claim 1 , wherein the capsule is a clear golden brown color.

10 . The rupture-stable gelatin filled capsule of claim 9 , wherein the nutraceutical ingredients comprise polyunsaturated fatty acids, derived from omega 3-oils of fish, hill, green lipped mussel, algae, and/or plants.

11 . The rupture-stable gelatin filled capsule of claim 9 , further comprising lipid-based nutraceutical ingredients as filler materials, such as saw palmetto.

12 . The rupture-stable gelatin filled capsule of claim 9 , containing nutraceutical ingredients such as garlic, valerian, milk thistle, N-acetyl cysteine, S-adenosylmethionine, quercetin, pyrroloquinoline quinone (PQQ), alpha-lipoic acid, thiamine hydrochloride, thiamine mononitrate, Vitamin C, Vitamin K1, Vitamin K2, Vitamin K3, Vitamin D2, Vitamin D3, Vitamin A and beta-carotene, lycopene, Vitamin E TPGS, Vitamin E forms including mixed tocopherols, chamomile, turmeric, ginger, dill weed, mineral forms of iron, copper, and manganese to be used as softgel filler materials.

13 . The rupture-stable gelatin filled capsule of claim 1 , wherein the capsule withstands disintegration for 60 minutes after placement in simulated gastric fluid.

14 . The rupture-stable gelatin filled capsule of claim 13 , wherein the capsule disintegrates upon placement into simulated intestinal fluid within 60 minutes.

15 . A method of producing a rupture-stable gelatin filled capsule, comprising the steps of:

a) mixing glycerin, gelatin, and water in ratios of 1:2.5:2 by weight;

b) controlling the temperature of the mixture with a temperature controlled melter to approximately 150-200° F.;

c) heating the mixture until the gelatin has completely melted;

d) allowing the mixture to cool down to temperatures between 135-150° F.;

e) adding 0.1%-5% by weight of aqueous D-xylose to the hot gelatin mixtures;

f) mixing the resulting xylose-gelatin mixture for at least 15 minutes at temperatures above 140° F.;

g) adding water to the xylose-gelatin mixture to maintain viscosities of 10,000-16,000 cps; and

h) encapsulating nutrapharmaceuticals within the xylose-gelatin mixture.

Assignments (8)