IP Library Granted Patent US 11,324,945
Granted Patent B2
US 11,324,945 · App. 16/514,772 · Granted May 10, 2022

Neural interface system

Inventors: Rio J. Vetter (Ypsilanti, MI); Daryl R. Kipke (Dexter, MI); David Pellinen (Ann Arbor, MI); David J. Anderson (Ann Arbor, MI); Jamille Farraye Hetke (Brooklyn, MI)
Assignee: Medtronic Bakken Research Center B.V.
A61N1/0534A61N1/0539B29C45/14639A61B5/24A61N1/36082B29K2083/00B29L2031/753
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Quick Facts
Patent No.
US 11,324,945
App. No.
16/514,772
Granted
May 10, 2022
Kind
B2
Abstract

The neural interface system of the preferred embodiments includes an electrode array having a plurality of electrode sites and a carrier that supports the electrode array. The electrode array is coupled to the carrier such that the electrode sites are arranged both circumferentially around the carrier and axially along the carrier. A group of the electrode sites may be simultaneously activated to create an activation pattern. The system of the preferred embodiment is preferably designed for deep brain stimulation, and, more specifically, for deep brain stimulation with fine electrode site positioning, selectivity, tunability, and precise activation patterning. The system of the preferred embodiments, however, may be alternatively used in any suitable environment (such as the spinal cord, peripheral nerve, muscle, or any other suitable anatomical location) and for any suitable reason.

Claims (29)

1. A neural interface system comprising:

a deep brain stimulation (DBS) electrode array having a plurality of electrode sites that electrically communicate with their surroundings, wherein the plurality of electrode sites includes a subset of one or more stimulation electrode sites and a subset of one or more recording electrode sites;

a carrier that supports the electrode array, wherein the electrode array is coupled to the carrier such that the plurality of electrode sites are arranged both circumferentially around the carrier and axially along the carrier; and

a plurality of conductive interconnects of varying length coupled to the respective electrode sites of the electrode array, wherein a resistance of each of the plurality of conductive interconnects is generally equal.

2. The neural interface system of claim 1 , wherein a size of an electrode site of the stimulation electrode sites is different than a size of an electrode site of the recording electrode sites.

3. The neural interface system of claim 1 , wherein a number of electrode sites included in the subset of stimulation electrode sites is greater than a number of electrode sites included in the subset of recording electrode sites.

4. The neural interface system of claim 1 , wherein the subset of stimulation electrode sites includes a plurality of stimulation electrode sites positioned circumferentially around a particular axial location along the carrier.

5. The neural interface system of claim 4 , wherein each of the plurality of stimulation electrode sites positioned circumferentially around the particular axial location along the carrier is independently activatable.

6. The neural interface system of claim 1 , further comprising circuitry operably connected to the DBS electrode array, the circuitry configured to generate stimulation pulses for delivery via the one or more stimulation electrode sites.

7. The neural interface system of claim 6 , wherein the circuitry is further configured to generate the stimulation pulses based on input signals received via the one or more recording electrode sites.

8. The neural interface system of claim 6 , wherein the circuitry is implantable in a cranial burr-hole chamber.

9. The neural interface system of claim 8 , further comprising a connector configured to connect the DBS electrode array to the circuitry in the cranial burr-hole chamber.

10. A deep brain stimulation (DBS) lead comprising:

an electrode array having a plurality of electrode sites that electrically communicate with their surroundings, wherein the plurality of electrode sites includes a subset of one or more stimulation electrode sites and a subset of one or more recording electrode sites;

a carrier that supports that electrode array, wherein the electrode array is coupled to the carrier such that the plurality of electrode sites are arranged both circumferentially around the carrier and axially along the carrier; and

a plurality of conductive interconnects of varying length coupled to the respective electrode sites of the electrode array, wherein a resistance of each of the plurality of conductive interconnects is generally equal.

11. The DBS lead of claim 10 , wherein a size of an electrode site of the stimulation electrode sites is different than a size of an electrode site of the recording electrode sites.

12. The DBS lead of claim 10 , wherein a number of electrode sites included in the subset of stimulation electrode sites is greater than a number of electrode sites included in the subset of recording electrode sites.

13. The DBS lead of claim 12 , further comprising a connector configured to connect the electrode array to an electrical subsystem locatable in a cranial burr-hole chamber.

14. The DBS lead of claim 10 , wherein the subset of stimulation electrode sites includes a plurality of stimulation electrode sites positioned circumferentially around a particular axial location along the carrier.

15. The DBS lead of claim 14 , wherein each of the plurality of stimulation electrode sites positioned circumferentially around the particular axial location along the carrier is independently activatable.

16. A deep brain stimulation (DBS) lead comprising:

an electrode array having a plurality of electrode sites that electrically communicate with their surroundings, wherein the plurality of electrode sites includes a subset of one or more stimulation electrode sites;

a carrier that supports that electrode array, wherein the electrode array is coupled to the carrier such that the plurality of electrode sites are arranged both circumferentially around the carrier and axially along the carrier; and

a plurality of conductive interconnects of varying length coupled to the respective electrode sites of the electrode array, wherein a resistance of each of the plurality of conductive interconnects is generally equal.

17. The DBS lead of claim 16 , wherein the plurality of electrode sites includes a subset of one or more recording electrode sites, and wherein a size of an electrode site of the stimulation electrode sites is different than a size of an electrode site of the recording electrode sites.

18. The DBS lead of claim 16 wherein a number of electrode sites included in the subset of stimulation electrode sites is greater than a number of electrode sites included in the subset of recording electrode sites.

19. The DBS lead of claim 16 , wherein the subset of stimulation electrode sites includes a plurality of stimulation electrode sites positioned circumferentially around a particular axial location along the carrier.

20. The DBS lead of claim 19 , wherein each of the plurality of stimulation electrode sites positioned circumferentially around the particular axial location along the carrier is independently activatable.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 17, 2019
From: VETTER, RIO J.; KIPKE, DARYL R.; PELLINEN, DAVID; ANDERSON, DAVID; HETKE, JAMILLE F.
To: NEURONEXUS TECHNOLOGIES, INC.
Reel/Frame 049782/0496 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 17, 2019
From: NEURONEXUS TECHNOLOGIES, INC.
To: SAPIENS STEERING BRAIN STIMULATION B.V.
Reel/Frame 049782/0511 →
MERGER Recorded Jul 17, 2019
From: SAPIENS STEERING BRAIN STIMULATION B.V.
To: MEDTRONIC BAKKEN RESEARCH CENTER B.V.
Reel/Frame 049784/0864 →