IP Library Granted Patent US 12,370,340
Granted Patent B2
US 12,370,340 · App. 16/521,056 · Granted Jul 29, 2025

Brain computer interface based pain management therapy

Inventors: Kern Bhugra (Santa Cruz, CA); Eric C. Leuthardt (St. Louis, MO)
Assignee: NeuroLutions, Inc.
A61M21/02A61B5/377A61B5/383A61M2021/0022A61M2021/0066A61M2205/05A61M2205/3606A61M2205/3673A61M2205/50A61M2205/52A61M2230/10
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Quick Facts
Patent No.
US 12,370,340
App. No.
16/521,056
Granted
Jul 29, 2025
Kind
B2
Abstract

Systems, devices and methods are provided for conducting a pain management therapy session, which includes performing a BCI training session utilizing feedback to train a subject to generate defined brain signals to assist the subject in managing and/or relieving pain, and applying a stimulus to the subject, in connection with the BCI training session, at a location that is near the source of pain and/or within the nervous system pain pathway to the source of pain.

Claims (24)

1. A method of conducting a pain management therapy session, comprising:

applying, to a subject and at a location that is near to a source of pain and/or within a nervous system pain pathway to the source of pain, a single stimulation device, wherein the stimulation device is in signal communication with a brain computer interface (“BCI”) control system;

using a brain signal acquisition system with skin surface electrodes to continuously acquire brain signals from the subject's brain;

transmitting the brain signals to the BCI control system;

evaluating, by the BCI control system, the brain signals in comparison to an alpha brain rhythm;

applying, by the stimulation device and as a neurofeedback response to an evaluation of the brain signals in comparison to the alpha brain rhythm, a single stimulus to the subject at the location that is near to the source of pain and/or within the nervous system pain pathway to the source of pain; and

receiving results of a decrease in power of alpha rhythm brain waves produced by the subject.

2. The method of claim 1 , wherein the single stimulus applied to subject by the stimulation device comprises a proprioceptive stimulus.

3. The method of claim 1 , wherein the single stimulus applied to the subject by the stimulation device is generated by a vibration generating element of the stimulation device.

4. The method of claim 3 , wherein the vibration generating element is a wearable vibration generating element.

5. The method of claim 1 , comprising:

training the subject before conducting the pain management therapy session to obtain the alpha brain rhythm of the subject.

6. The method of claim 1 , comprising determining suitability of the subject for pain management therapy before conducting the pain management therapy session with the subject.

7. The method of claim 6 , wherein determining suitability comprises performing a decorrelation test on the subject.

8. The method of claim 1 , wherein applying the single stimulus is used to train the subject to manage pain.

9. A system for conducting a pain management therapy session, comprising:

a brain signal acquisition system for continuously acquiring brain signals from a a subject's brain;

a single stimulation device configured and adapted to be applied to the subject at a single location within a pain pathway of a source of pain; and

a brain computer interface (“BCI”) control/processing module programmed to:

receive the brain signals;

evaluate the brain signals in comparison to an alpha brain rhythm;

in response to the evaluation of the brain signals in comparison to the alpha brain rhythm, cause an activation of the stimulation device to generate a single stimulus to train the subject; and

receive results of a decrease in power of alpha rhythm brain waves produced by the subject.

10. The system of claim 9 , wherein the stimulation device is configured to activate in response to neurofeedback of the subject.

Assignments (2)
SECURITY INTEREST Recorded Nov 19, 2025
From: KANDU, INC.; KANDU HEALTH, INC.; NEUROLUTIONS, INC.
To: ANKURA TRUST COMPANY, LLC, AS COLLATERAL TRUSTEE
Reel/Frame 072963/0620 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2021
From: BHUGRA, KERN; LEUTHARDT, ERIC C.
To: NEUROLUTIONS, INC.
Reel/Frame 055163/0089 →
Continuity (1)
Related Publication 20210023330A1 · Jan 28, 2021
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