System and methods for processing analyte sensor data for sensor calibration
Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
1. An analyte monitoring system comprising:
processing electronics configured to receive a signal generated by a transcutaneous analyte sensor having one or more sensor electrical contacts on an ex vivo portion of the transcutaneous analyte sensor; and
a display operably connected to the processing electronics, wherein the display is configured to display at least one estimated analyte concentration of a host based at least in part on the signal;
wherein the processing electronics are configured to:
generate digital data based at least in part on the received signal;
calibrate at least some of the generated digital data using a first conversion function;
calibrate at least some of the generated digital data using a second conversion function different from the first conversion function; and
selecting between the first conversion function and the second conversion function for use in calibrating generated digital data based at least in part on time of day;
wherein the processing electronics are configured to generate the at least one estimated analyte value based at least in part on the calibrated digital data.
2. The analyte monitoring system of claim 1 , wherein the first conversion function and the second conversion function each comprise a sensor sensitivity value.
3. The analyte monitoring system of claim 1 , wherein the first conversion function and the second conversion function each comprise a baseline value.
4. The analyte monitoring system of claim 2 , wherein the first conversion function and the second conversion function each comprise a baseline value.
5. A method of monitoring an analyte concentration in a host, the method comprising:
generating a signal from an implanted transcutaneous analyte sensor during a sensor session of the host;
generating digital data based at least in part on the signal;
measuring a time of day during the sensor session;
selecting between a first calibration conversion function and a second calibration conversion function based at least in part on the measured time of day;
calibrating the generated digital data using the selected calibration conversion function;
generating at least one estimated analyte concentration of the host based at least in part on the calibrated digital data; and
displaying, on a display, the at least one estimated analyte concentration.