IP Library Granted Patent US 11,275,094
Granted Patent B2
US 11,275,094 · App. 16/554,969 · Granted Mar 15, 2022

Biological sample processing

Inventors: Elizabeth A. Holmes (San Francisco, CA); Adrit Lath (Sunnyvale, CA)
Assignee: Labrador Diagnostics LLC
G01N35/00732B01L3/545G01N35/0099G01N35/021G01N35/1002B01L2200/16B01L2300/021B01L2300/022G01N2035/00346G01N2035/00752G01N2035/00851G01N2035/0436G01N2035/0489Y10S901/01Y10S901/41
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Quick Facts
Patent No.
US 11,275,094
App. No.
16/554,969
Granted
Mar 15, 2022
Kind
B2
Abstract

Systems and methods are provided for processing a biological sample. In one embodiment, the method comprises receiving a sample vessel containing the sample; retrieving information from an information storage unit associated with the sample; using said information for selecting at least one cartridge front at least two or more different cartridges, each configured for use with a sample processing device; loading at least one or more reagents onto the cartridge, wherein the one or more reagents to be added are selected based at least in part on the information or instructions derived from the information; and placing the sample vessel in the cartridge.

Claims (34)

1. A method for processing a biological sample, the method comprising:

receiving a sample vessel containing the sample;

retrieving information from an information storage unit associated with the sample;

using said information for selecting at least one cartridge from at least two or more different cartridges, each configured for use with a sample processing device; and

using an automated robotic system to load the cartridge and the sample vessel onto a robotic transport assembly for operably coupling a cartridge assembly location with a sample processing location of the sample processing device.

2. The method of claim 1 wherein retrieving comprises using optical scanning to obtain information from the information storage unit.

3. The method of claim 1 wherein retrieving comprises using electromagnetic techniques to obtain information from the information storage unit.

4. The method of claim 1 wherein the information storage unit comprises a bar code.

5. The method of claim 1 wherein the information storage unit comprises a QR code.

6. The method of claim 1 further comprising communicating the information from to an external server.

7. The method of claim 1 wherein the information comprises information regarding components to be included in the cartridge.

8. The method of claim 1 wherein at least one of the cartridges is partially loaded with some components prior to being selected.

9. The method of claim 1 wherein the information comprises information specifying which tests are to be performed on the sample.

10. The method of claim 1 wherein the cartridge comprises at least one absorbent pad.

11. The method of claim 1 wherein the two or more different cartridges each defines one or more locations for receiving one or more reagent vessels.

12. The method of claim 1 wherein the two or more different cartridges each defines one or more locations for receiving one or more diluent vessels.

13. The method of claim 1 wherein the two or more different cartridges each defines one or more locations for receiving one or more pipette tips.

14. The method of claim 1 wherein the two or more different cartridges each defines one or more locations for receiving one or more reaction vessels.

15. The method of claim 1 wherein the two or more different cartridges each defines one or more locations for receiving one or more arrays of reaction vessels.

16. The method of claim 1 wherein the two or more different cartridges each defines one or more locations for receiving one or more arrays of cuvettes.

17. The method of claim 1 further comprising a plurality of sample processing devices at the sample processing location, wherein the sample processing devices are arranged in an array configuration.

18. The method of claim 1 further comprising a plurality of sample processing devices at the sample processing location, wherein the sample processing devices are arranged in a semi-circular array configuration about a cartridge loading assembly.

19. A method for processing a biological sample, the method comprising:

receiving a sample vessel containing the sample;

retrieving information from an information storage unit associated with the sample;

communicating the information to an external server;

using said information for selecting at least one cartridge from at least two or more different cartridges, each configured for use with a sample processing device; and

using an automated robotic system to load the cartridge and the sample vessel onto a robotic transport assembly for operably coupling a cartridge assembly location with a sample processing location of the sample processing device.

20. A method for processing a biological sample, the method comprising:

receiving a sample vessel containing the sample;

retrieving information from an information storage unit associated with the sample;

using said information for selecting at least one cartridge from at least two or more different cartridges, each configured for use with a sample processing device; and

using an automated robotic system to load the cartridge and the sample vessel onto a robotic transport assembly for operably coupling a cartridge assembly location with a sample processing location of the sample processing device.

wherein the two or more different cartridges each has a different configuration for holding reagents.

Assignments (3)
CHANGE OF NAME Recorded Apr 15, 2020
From: THERANOS IP COMPANY, LLC
To: LABRADOR DIAGNOSTICS LLC
Reel/Frame 052410/0432 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2019
From: HOLMES, ELIZABETH A.; LATH, ADRIT
To: THERANOS, INC.
Reel/Frame 050210/0802 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2019
From: THERANOS, INC.
To: THERANOS IP COMPANY, LLC
Reel/Frame 050217/0941 →
Continuity (4)
Continuation 14855249 · Sep 15, 2015
Continuation PCTUS2014032092 · Mar 27, 2014
Provisional Application 61805925 · Mar 27, 2013
Related Publication 20200096527A1 · Mar 26, 2020