Botanical antioxidants
A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the leaf of a plant from the genus Vaccinium.
1. A method of inhibiting oxidation-induced DNA damage in a subject in need thereof comprising:
administering an effective amount of a composition comprising a botanical extract of a leaf of Vaccinium macrocarpon to said subject,
wherein the botanical extract is present in the composition in an amount of about 40.0 μg/mL to about 150.0 μg/mL,
wherein the botanical extract is free of anthocyanins, and
wherein the botanical extract has a flavonoid content of at least about twenty times greater than that of the fruit of Vaccinum macrocarpon.
2. The method according to claim 1 , wherein the botanical extract of the leaf of Vaccinium macrocarpon inhibits γ-H2AX activity, thereby inhibiting oxidation-induced DNA damage in said subject.
3. The method according to claim 1 , wherein the composition is administered in form for oral ingestion.
4. The method according to claim 1 , wherein the composition is a dietary supplement.
5. The method according to claim 4 , wherein the dietary supplement is in solid dosage form.