IP Library Granted Patent US 11,141,446
Granted Patent B2
US 11,141,446 · App. 16/561,596 · Granted Oct 12, 2021

Anti-inflammatory botanical extract

Inventors: Jatinder Rana (Grand Rapids, MI); Kylie Mitchell (Pennington, NJ)
Assignee: Innophos, LLC
A61K36/45A61K9/0014A61K9/0053A61K31/353A61P29/00
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Quick Facts
Patent No.
US 11,141,446
App. No.
16/561,596
Granted
Oct 12, 2021
Kind
B2
Abstract

A botanical extract that exhibits anti-inflammatory activity, wherein the botanical extract is at least an extract from the leaf of Vaccinium macrocarpon.

Claims (12)

1. A method of inhibiting inflammation in a subject in need thereof comprising:

administering an effective amount of a composition comprising a botanical extract of the leaf of Vaccinium macrocarpon to said subject,

wherein the botanical extract is present in the composition in an amount of about 50.0 μg/mL to about 500.0 μg/mL, and

wherein the botanical extract is free of anthocvanins, and

wherein the botanical extract has a flavonoid content of at least about twenty times greater than that of the fruit of Vaccinum macrocarpon.

2. The method according to claim 1 , wherein the composition inhibits COX-1 activity.

3. The method according to claim 1 , wherein the composition inhibits COX-2 activity.

4. The method according to claim 1 , wherein the composition inhibits 5-LOX activity.

5. The method according to claim 1 , wherein the composition is administered in form for oral ingestion.

6. The method according to claim 1 , wherein the composition is a dietary supplement.

7. The method according to claim 6 , wherein the dietary supplement is in solid dosage form.

8. The method according to claim 1 , wherein the composition is a topical composition.

Assignments (2)
SECURITY INTEREST Recorded Jan 6, 2025
From: INNOPHOS, LLC
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT
Reel/Frame 069749/0211 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 27, 2021
From: INNOPHOS, INC.
To: INNOPHOS, LLC
Reel/Frame 057925/0188 →
Continuity (2)
Provisional Application 62728125 · Sep 7, 2018
Related Publication 20200078432A1 · Mar 12, 2020