Stable pharmaceutical composition and methods of using same
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
1. A pharmaceutical composition, comprising: omega-3 fatty acids in free acid form including (a) eicosapentaenoic acid in an amount selected from about 925 mg, about 950 mg, and about 975 mg; and (b) docosapentaenoic acid in an amount of about 5%, by weight, of total fatty acids in the pharmaceutical composition.
2. The pharmaceutical composition of claim 1 , wherein the eicosapentaenoic acid is present in an amount of about 925 mg.
3. The pharmaceutical composition of claim 1 , wherein the eicosapentaenoic acid is present in an amount of about 950 mg.
4. The pharmaceutical composition of claim 1 , wherein the eicosapentaenoic acid is present in an amount of about 975 mg.
5. The pharmaceutical composition of claim 1 , wherein the pharmaceutical composition is present in one or more dosage units.
6. The pharmaceutical composition of claim 5 , wherein the one or more dosage units comprise capsules.
7. A method of reducing triglycerides in a subject in need thereof comprising, administering to the subject daily the pharmaceutical composition of claim 1 .
8. The method of claim 7 , wherein the subject has very high serum triglycerides.