BIOMEDICAL PATCH AND DELIVERY SYSTEM
A multi-laminar repair matrix for repairing a tissue defect may comprise a top patch and a bottom compliant patch. The bottom compliant patch may be compressed and sized to fit through a tissue defect, and expand to a substantially planar state after being implanted to the tissue defect. The top and/or bottom patch may include adhesives. A tool for implanting a patch to a tissue defect may include a shaft, a plurality of arms pivotally connected to the shaft, and a control. The control may be configured to radially expand the plurality of arms upon actuation of the control.
1 .- 29 . (canceled)
30 . A repair matrix for repairing a tissue defect, the repair matrix comprising:
a top flexible patch, the top flexible patch comprising material that facilitates tissue growth;
a bottom flexible patch, the bottom flexible patch comprising material that facilitates tissue growth, wherein a periphery of the bottom flexible patch comprises an adhesive; and
a connecting portion connecting a non-peripheral portion of the top flexible patch with a non-peripheral portion of the bottom flexible patch, the connecting portion comprising a height adapted to prevent adhesion of the bottom flexible patch to the top flexible patch,
wherein the top flexible patch comprises a first biodegrade time, the bottom flexible patch comprises a second biodegrade time, and the adhesive comprises a third biodegrade time, wherein the third biodegrade time is longer than the first biodegrade time and the second biodegrade time.
31 . The repair matrix of claim 1 , wherein one or both of the top flexible patch and the bottom flexible patch comprises electro-spun fibers.
32 . The repair matrix of claim 1 , wherein one or both of the top flexible patch and the bottom flexible patch comprises wholly synthetic dural substitute material.
33 . The repair matrix of claim 1 , wherein one or both of the top flexible patch and the bottom flexible patch is configured to biodegrade after being implanted to tissue surrounding a tissue defect.
34 . The repair matrix of claim 33 , wherein the tissue defect is a dural defect.
35 . The repair matrix of claim 1 , wherein a peripheral portion of the top flexible patch comprises an adhesive.
36 . The repair matrix of claim 1 , wherein a shape of the top flexible patch substantially matches a shape of the bottom flexible patch.
37 . The repair matrix of claim 1 , wherein a shape of the top flexible patch is different from a shape of the bottom flexible patch.
38 . The repair matrix of claim 1 , wherein one or both of the top flexible patch and the bottom flexible patch comprises shape memory material.
39 . The repair matrix of claim 1 , wherein the height of the connecting portion is adjustable to substantially match a width of tissue surrounding a tissue defect.
40 . The repair matrix of claim 1 , wherein the connecting portion connecting the non-peripheral portion of the top flexible patch with the non-peripheral portion of the bottom flexible patch comprises an adhesive.
41 . The repair matrix of claim 1 , wherein the connecting portion connecting the non-peripheral portion of the top flexible patch with the non-peripheral portion of the bottom flexible patch comprises a same material as the material of the top flexible patch and/or the bottom flexible patch.
42 . A kit for repairing a dural defect, comprising:
a sterile packet containing a plurality of biodegradable patches, wherein the plurality of biodegradable patches comprise varying sizes, wherein each of the plurality of biodegradable patches comprises material that facilitates tissue growth, wherein a periphery of one or more of the plurality of biodegradable patches comprises an adhesive for adhering the biodegradable patch to a surface of tissue surrounding a tissue defect, and wherein the one or more of the plurality of biodegradable patches comprises a first biodegrade time, and the adhesive of the one or more of the plurality of biodegradable patches comprises a second biodegrade time, wherein the second biodegrade time is longer than the first biodegrade time.
43 . The kit of claim 42 , wherein each of the plurality of biodegradable patches comprises a shape that is square, rectangular, circular, triangular, elliptical, hexagonal, or quadrilateral.
44 . The kit of claim 42 , wherein each of the plurality of biodegradable patches comprises shape memory material.
45 . The kit of claim 42 , wherein each of the plurality of biodegradable patches comprises electro-spun fibers.
46 . The kit of claim 42 , wherein each of the plurality of biodegradable patches comprises wholly synthetic dural substitute material.
47 . A repair matrix for repairing a tissue defect, comprising:
a flexible patch, the flexible patch comprising a material formed by electrospinning that facilitates tissue growth, wherein the flexible patch in a first state is configured to be compressed to facilitate implantation of the flexible patch to tissue surrounding a tissue defect, and the flexible patch in a second state is configured to be expanded such that the flexible patch substantially conforms to a curvature of the tissue surrounding the tissue defect,
wherein a periphery of the flexible patch in the second state comprises an adhesive for adhering the flexible patch to the tissue surrounding the tissue defect,
wherein the flexible patch comprises a first biodegrade time, and the adhesive comprises a second biodegrade time, wherein the second biodegrade time is longer than the first biodegrade time.
48 . The repair matrix of claim 47 , wherein the flexible patch is configured to biodegrade after being implanted to the tissue surrounding a tissue defect.
49 . The repair matrix of claim 47 , wherein the flexible patch comprises wholly synthetic dural substitute material.