IP Library Granted Patent US 11,226,387
Granted Patent B2
US 11,226,387 · App. 16/593,090 · Granted Jan 18, 2022

Magnetic resonance imaging apparatus and image processing apparatus

Inventor: Kousuke Itou (Tokyo, JP)
Assignee: HITACHI, LTD.
G01R33/5608G01R33/543G01R33/5611G01R33/5635A61B5/055G01R33/546
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Quick Facts
Patent No.
US 11,226,387
App. No.
16/593,090
Granted
Jan 18, 2022
Kind
B2
Abstract

Provided is a new scheme for applying a CS technology in a technology for imaging a target tissue based on a difference from a reference image or a control image. In this way, an imaging time is shortened. A measurement unit of an MRI apparatus executes a first imaging sequence and a second imaging sequence having different contrasts for a target, and measures a nuclear magnetic resonance signal from a subject in each of the imaging sequences. In the second imaging sequence, under-sampling is performed, and a nuclear magnetic resonance signal having a small number of samples is measured. The image processing unit restores measurement data including a nuclear magnetic resonance signal obtained by under-sampling using compressed sensing. At this time, data restoration including a term for minimizing an L1 norm is performed for a difference image between an image obtained by execution of the first imaging sequence and an image obtained by execution of the second imaging sequence.

Claims (34)

1. A magnetic resonance imaging (MRI) apparatus comprising:

a measurement unit that executes a first imaging sequence and a second imaging sequence having different contrasts for a target, the measurement unit configured to measure a nuclear magnetic resonance signal from a subject in each of the imaging sequences;

a control unit that controls an operation of the measurement unit;

an image processing unit that creates an image of the target using measurement data including the nuclear magnetic resonance signal measured in each of the first imaging sequence and the second imaging sequence;

wherein the control unit controls the measurement unit such that the measurement unit under-samples the measurement data obtained during the second imaging sequence;

wherein the image processing unit includes:

a data restoration unit that restores the measurement data obtained by under-sampling using compressed sensing;

a conversion unit that converts measurement data and image data; and

a difference image computation unit that computes a difference between images obtained by different imaging sequences; and

wherein the data restoration unit performs data restoration to minimize an L1 norm for a difference image between an image obtained by execution of the first imaging sequence and an image obtained by execution of the second imaging sequence,

wherein echo signals of a set number of encoding steps are collected in both of the first imaging sequence and the second imaging sequence, the echo signals being included within the image data;

wherein the first imaging sequence is a time of flight (TOF) sequence that does not include a pre-saturation pulse, and the second imaging sequence is a TOF sequence that includes a pre-saturation pulse; and

wherein the control unit controls the measurement unit to alternately measure a plurality of repetition times of the first imaging sequence and measure one or more repetition times of the second imaging sequence, wherein a number of the plurality of repetition times is changed based on a double speed number of the second imaging sequence.

2. The MRI apparatus according to claim 1 , wherein the control unit controls the measurement unit to fully sample the measurement data obtained during the first imaging sequence.

3. The MRI apparatus according to claim 1 , wherein the data restoration unit performs data reproduction using compressed sensing according to Equation (1), specified as follows:

argmin(∥ F u I wSAT −y∥ 2 2 +λ|I woSAT | 1   (1);

wherein I woSAT and I wSAT respectively represent an image obtained by the first imaging sequence and an image obtained by the second imaging sequence, F u represents a Fourier transform, y denotes measurement data obtained in the second imaging sequence, and λ is a coefficient.

4. The MRI apparatus according to claim 3 , wherein Equation (1) further includes at least one of a term that minimizes an L1 norm of a sparse transformation space and a term that minimizes a total variation.

5. The Mill apparatus according to claim 1 , wherein the target is a head blood vessel of the subject, and the pre-saturation pulse is a pulse for selectively exciting a columnar region.

6. The Mill apparatus according to claim 1 , wherein the first imaging sequence and the second imaging sequence correspond to non-contrast angiographic imaging sequences, and the second imaging sequence includes a pulse for labeling the target.

7. An image processing apparatus for performing image reconstruction using compressed sensing, the image processing apparatus comprising:

a receiving unit that receives first measurement data obtained by full sampling in an MRI apparatus and second measurement data obtained by under-sampling under a different imaging condition from an imaging condition of the first measurement data;

a conversion unit that respectively converts the first measurement data and the second measurement data into first image data and second image data; and

a data restoration unit that restores under-sampled measurement data;

wherein the data restoration unit performs a calculation using compressed sensing to minimize an L1 norm for difference data, the difference data determined between the first image data and the second image data;

wherein each of the first measurement data and the second measurement data are respectively obtained from a first imaging sequence and a second imaging sequence, and

wherein echo signals of a set number of encoding steps are collected in both of the first imaging sequence and the second imaging sequence, the echo signals being included within at least one of the first image data and the second image data;

wherein the first imaging sequence is a time of flight (TOF) sequence that does not include a pre-saturation pulse, and the second imaging sequence is a TOF sequence that includes a pre-saturation pulse; and

wherein a control unit controls a measurement unit to alternately measure a plurality of repetition times of the first imaging sequence and measure one or more repetition times of the second imaging sequence, wherein a number of the plurality of repetition times is changed based on a double speed number of the second imaging sequence.

8. The image processing apparatus according to claim 7 , further comprising:

a difference image computation unit that obtains a difference between image data obtained by converting the second measurement data restored by the data restoration unit and the first image data, and computes a difference image.

9. The MRI apparatus according to claim 1 , wherein the measurement unit comprises a radiofrequency (RF) coil for detecting a signal generated from a subject, the RF coil comprising a plurality of receiving coils having different sensitivity distributions, and wherein the measurement unit executes thinning imaging at a thinning rate corresponding to a number of receiving coils.

10. The MRI apparatus according to claim 9 , wherein the sensitivity distributions are used to reconstruct the image at a time of converting the measurement data into the image data.

11. The MRI apparatus according to claim 1 , wherein the second imaging sequence is executed during a repetition of the first imaging sequence.

Assignments (4)
MERGER Recorded Jan 10, 2025
From: FUJIFILM HEALTHCARE CORPORATION
To: FUJIFILM CORPORATION
Reel/Frame 069869/0951 →
MERGER Recorded Oct 11, 2024
From: FUJIFILM HEALTHCARE CORPORATION
To: FUJIFILM CORPORATION
Reel/Frame 070607/0722 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 15, 2022
From: HITACHI, LTD.
To: FUJIFILM HEALTHCARE CORPORATION
Reel/Frame 059115/0985 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 4, 2019
From: ITOU, KOUSUKE
To: HITACHI, LTD.
Reel/Frame 050626/0040 →