IP Library Granted Patent US 12,053,003
Granted Patent B2
US 12,053,003 · App. 16/617,867 · Granted Aug 6, 2024

Animal feed supplement

Inventors: Carl Jorg Michael Graz (Abertillery Blaenau Gwent, GB); Albrecht Joerg Matthias Miller (Abertillery Blaenau Gwent, GB)
Assignee: MOTTRAL SA
A23K20/111A23K10/30A23K20/105A23K20/121A23K50/10
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Quick Facts
Patent No.
US 12,053,003
App. No.
16/617,867
Granted
Aug 6, 2024
Kind
B2
Abstract

An animal feed supplement and an animal feed composition including said animal feed supplement, and methods of making and using said animal feed supplement and animal feed composition. The animal feed supplement includes at least one organosulfur compound and at least one phenolic compound.

Claims (20)

1. A method of using a supplement in feeding a ruminant animal, the method comprising:

administering the supplement to the ruminal animal in feed for the ruminant animal, the supplement including allicin and a combination of naringin and neohesperidin, wherein a ratio of naringin to neohesperidin is from 0.5:5 to 3:1, a ratio of allicin to the combination of naringin and neohesperidin is from 16:1 to 1:30, the administering of the supplement directly and detectably reduces methane production in the ruminant animal, and such combination of allicin, naringin, and neohesperidin is synergistic compared to administration of an identical composition that lacks any of allicin, naringin, or neohesperidin.

2. The method of claim 1 , wherein the supplement further includes alliin, allylpropyl disulfide, diallyl trisulfide, s-allylcysteine, vinyldithiines, and diallyl disulfide.

3. The method of claim 1 , wherein the supplement further includes a non-bioflavonoid phenolic compound independently selected from phenolic acid, hydroxycinnamic acids, coumarins, stilbenoids, anthraquinones, lignans, lignins, tannins, polyphenolic proteins, and polyphenols.

4. The method of claim 1 , wherein the supplement further includes at least one phenolic compound independently selected from the group consisting of eriocitrin, isonaringin, naringenin, hesperidin, roifolin, diosmin, didymin, hesperetin, poncirin, catechin, rutin, acacetin, genistein, kaempferol, quercetin, epicatechin, gallocatechin, epigallocatechin, catechin gallate, epicatechin gallate, epigallocatechin gallate, gallocatechin gallate, coumaric acid, cinnamic acid, gallic acid, elagic acid, protocathechic acid, chlorogenic acid, caffeic acid, ferullic acid, punicalagin, and punicalin.

5. The method of claim 1 , wherein the supplement further includes catechin, rutin, acacetin, genistein, kaempferol, coumaric acid, cinnamic acid, gallic acid, elagic acid, protocathechuic acid, chlorogenic acid, caffeic acid, ferullic acid, punicalagin, punicalin, or combinations thereof.

6. The method of claim 1 , wherein the supplement further includes gallocatechin, catechin gallate, epicatechin, epigallocatechin, epigallocatechin, epicatechin gallate, epigallocathecin gallate, kaempferol, quercetin, or combinations thereof.

7. The method of claim 1 , wherein the naringin and neohesperidin are from a plant of Citrus spp.

8. The method of claim 1 , wherein the feed comprises from about 0.0001 wt % to about 10 wt % of allicin based on a dry weight of the feed.

9. The method of claim 8 , wherein the feed comprises from about 0.0001 wt % to about 10 wt % of the combination of naringin and neohesperidin based on a dry weight of the feed.

10. The method of claim 1 , wherein the feed is a concentrate animal feed composition, a roughage animal feed composition, or a mixture thereof.

11. The method of claim 1 , wherein the supplement is consumed by a ruminant animal selected from a cow, goat or sheep.

12. The method of claim 1 , wherein the supplement further includes at least one phenolic compound independently selected from the group consisting of eriocitrin, isonaringin, naringenin, hesperidin, hesperetin, and poncirin.

13. A method of using a supplement in feeding a ruminant animal, the method comprising:

administering the supplement to the ruminal animal in feed for the ruminant animal, the supplement consisting essentially of allicin and a combination of naringin and neohesperidin, wherein a ratio of naringin to neohesperidin is from 0.5:5 to 3:1, a ratio of allicin to the combination of naringin and neohesperidin is from 16:1 to 1:30, an administration of the allicin with the combination of naringin and neohesperidin directly and detectably reduces methane production in the ruminant animal, and such combination of allicin, naringin, and neohesperidin is synergistic compared to administration of an identical composition that lacks any of allicin, naringin, or neohesperidin.

14. The method of claim 1 , wherein a reduction of the methane production in the ruminant animal is a result of a combination of the allicin, naringin, and neohesperidin.

15. A method of using a supplement in feeding a ruminant animal, the method comprising: administering the supplement to the ruminal animal in feed for the ruminant animal, the supplement including allicin and a combination of naringin and neohesperidin wherein a ratio of naringin to neohesperidin is from 0.5:5 to 3:1, a ratio of allicin to the combination of naringin and neohesperidin is from 16:1 to 1:30, and the administering of the supplement directly and detectably reduces methane production in the ruminant animal at a level that is not observed upon administration of an otherwise identical composition that lacks any of allicin, naringin, or neohesperidin.

16. The method of claim 15 , wherein the naringin and neohesperidin are from a plant of Citrus spp.

17. The method of claim 15 , wherein the feed is a concentrate animal feed composition, a roughage animal feed composition, or a mixture thereof.

18. The method of claim 15 , wherein the supplement is consumed by a ruminant animal selected from a cow, goat or sheep.

Assignments (3)
NUNC PRO TUNC ASSIGNMENT Recorded Oct 20, 2025
From: MOOTRAL INNOVATIONS LIMITED (IN CREDITORS’ VOLUNTARY LIQUIDATION)
To: BIONEXUS LLC
Reel/Frame 073114/0803 →
NUNC PRO TUNC ASSIGNMENT Recorded Sep 17, 2024
From: MOOTRAL SA
To: MOOTRAL INNOVATIONS LIMITED
Reel/Frame 068605/0679 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2020
From: GRAZ, CARL JORG MICHAEL; MILLER, ALBRECHT JOERG MATTHIAS
To: MOOTRAL SA
Reel/Frame 051531/0034 →
Continuity (2)
Continuation PCTGB2017051562 · Jun 1, 2017
Related Publication 20200138056A1 · May 7, 2020