Method for biofilm dispersal
The present invention relates to a method for dispersing biofilm using mannose and its analogs.
1. A method to disperse existing biofilm comprising:
i. providing a biofilm wherein the biofilm comprises sulfate-reducing prokaryotes; and
ii. contacting the biofilm with a compound selected from the group consisting of mannose, 2-deoxy-D-glucose (2DG), methyl α-D-mannopyranoside (αMM), methyl α-D-glucopyranoside (αMG), and mixtures thereof to disperse the biofilm.
2. The method of claim 1 wherein biofilm comprises anaerobic bacteria.
3. The method of claim 1 wherein biofilm comprises sulfate reducing bacteria.
4. The method of claim 2 wherein the biofilm comprises Desulfovibrio vulgaris (ATCC 29579).
5. The method of claim 2 wherein the biofilm comprises Desulfovibrio desulfuricans (DSM 12129).