Detergent compositions comprising GH9 endoglucanase variants II

1. A detergent composition comprising an endoglucanase variant, wherein the variant comprises an alteration at one or more positions in a region selected from the group consisting of:

i) region 10 corresponding to amino acids 1 to 94 of SEQ ID NO: 2,

ii) region 11 corresponding to amino acids 106 to 114 of SEQ ID NO: 2,

iii) region 12 corresponding to amino acids 139 to 209 of SEQ ID NO: 2,

iv) region 13 corresponding to amino acids 252 to 266 of SEQ ID NO: 2,

v) region 14 corresponding to amino acids 302 to 338 of SEQ ID NO: 2,

vi) region 15 corresponding to amino acids 362 to 546 of SEQ ID NO: 2,

vii) region 16 corresponding to amino acids 596 to 611 of SEQ ID NO: 2,

viii) region 17 corresponding to amino acids 661 to 805 of SEQ ID NO: 2,

ix) region 18 corresponding to amino acids 829 to 838 of SEQ ID NO: 2,

x) region 19 corresponding to amino acids 1043 to 1055 of SEQ ID NO: 2, and

xi) combinations thereof;

wherein said variant has at least 90% and less than 100% sequence identity to SEQ ID NO: 2; wherein said variant has an improved storage stability in the detergent composition compared to a wild-type endoglucanase having a sequence identity that is identical to SEQ ID NO: 2.

2. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein said alteration at one or more positions is selected from the group consisting of alterations in positions: 17, 20, 51, 53, 55, 56, 60, 63, 79, 87, 186, 192, 302, 311, 313, 387, 388, 390, 403, 408, 410, 416, 448, 451, 471, 472, 476, 489, 507, 512, 515, 538, 598, 599, 602, 605, 609, 676, 688, 690, 694, 697, 698, 699, 711, 719, 754, 756, 760, 781, 786, 797, 833, 834, 835, 1048, and combinations thereof of SEQ ID NO: 2, wherein numbering is according to SEQ ID NO: 2.

3. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein said alteration at one or more positions is selected from the group consisting of: 517A, F20P, F20N, F20G, F20Y, K51Q, K51H, E53P, E53G, Y55M, V56M, Y60F, S63F, T87R, A186P, K192N, 1320D, 1302H, 1302V, 1302M, H311N, S313D, 1387T, K388R, K390Q, 1403Y, E408D, E408S , E408P, E408A, E408G, E408N, P410G, Q416S , Q416D, A448E, A448W, A448S, K451S, G471S, S472Y, D476R, Q489P, K507R, K512P, S515V, S538C, Y579W, S598Q, A599S, 1602T, 1602D, V603P, 5605T, G609E, D676H, A688G, Y690F, T694A, T697G, R698W, T699A, T711V, T711Y, W719R, K754R, V756H, V756Y, 5760G, T781M, N786K, T797S, A824D, N833D, Q834E, S835D, F1048W, and combinations thereof, wherein numbering is according to SEQ ID NO: 2.

4. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein said alteration at one or more positions is selected from the group consisting of alterations in positions: 17, 20, 302, 311, 313, 408, 476, 602, 688, 697, 719, and combinations thereof wherein numbering is according to SEQ ID NO: 2.

5. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein said alteration at one or more positions is selected from the group consisting of alterations in positions: S 517A, F20P, I 302D, H311N, S313D, E408D, D476R, I 602T, A688G, T697G, W719R, and combinations thereof wherein numbering is according to SEQ ID NO: 2.

6. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein the variant further comprises an alteration at one or more positions selected from the group consisting of alterations in positions: 216, 283, 346, 559, 564, 579, 636, 638, 651, 824, 848, 869, 880, 881, 883, 887, 892, 905, 906, 912, 921, 928, 934, 937, 948, 956, 999, 1037, and combinations thereof wherein numbering is according to SEQ ID NO: 2.

7. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein said alteration at one or more positions is selected from the group consisting of: N216D, N216Q, A283D, A346D, A559P, A559N, A564E, Y579W, S636K, S636N, F638N, A651P, A824D, N848D, A869V, R880K, V881T, V881Q, T883R, T887K, T892P, N905D, F906A, A912V, K921R, S928D, Y934G, A937E, K948R, Q956Y, T999R, A1037E, and combinations thereof wherein numbering is according to SEQ ID NO: 2.

8. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein the variant comprises one or more of the following set of substitutions:

F20Y + A448S + T781M

E408D + K451S

E408D + A448E

E408D

Y579W + E408D

9. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein the variant comprises one or more of the following set of substitutions:

S17A, F20P, N216D, A283D, H311N, E408D, Y579W, I602T,

A651P, A688G, T883R, F906A, Y934G, Q956Y

F20P, I302D, S313D, E408D, D476R, Y579W, S636K, T697G,

V756Y, V881Q, T887K, F906A, A937E

F20P, S313D, E408D, Y579W, S636K, A688G, T697G, N905D,

A937E

F20P, I302D, S313D, E408D, D476R, Y579W, S636K, T697G,

W719R, V756Y, V881Q, T887K, F906A, A937E

N216Q, S313D, E408D, D476R, Y579W, I602T, F638N, A651P,

T697G, W719R, R880K, T887K, K921R, Y934G

N216D, S313D, E408D, D476R, A564E, Y579W, I602T, F638N,

A651P, Y690F, T697G, W719R, V756H, N833D, A869V, R880K,

V881T, T887K, K921R, S928D, Y934G, T999R

F20P, I302D, S313D, E408D, D476R, Y579W, S636K, T697G,

W719R, V756Y, N848D, A869V, V881Q, T887K, N905D, F906A,

Q912V, A937E, T999R, F1048W

F20P, I302D, S313D, E408D, D476R, Q489P, Y579W, S636N,

T697G, W719R, V756Y, A824D, N848D, V881Q, T887K, F906A,

S928D, A937E

F20P, I302D, S313D, E408D, Q416S, D476R, Q489P, Y579W,

I602T, S636K, A651P, T697G, W719R, V756Y, A824D, N833D,

N848D, T883R, T887K, F906A, A937E

F20P, A186P, I302D, S313D, E408D, D476R, Q489P, Y579W,

A599S, I602T, S636K, A651P, T697G, W719R, V756Y, N848D,

T883R, T887K, F906A, A937E

N216D, S313D, E408D, D476R, Y579W, I602T, V603P, F638N,

A651P, A688G, T697G, W719R, V756H, R880K, T887K, K921R,

S928D, Y934G, K948R

F20P, K51Q, I302D, S313D, E408D, D476R, Q489P, Y579W,

I602T, S636K, A651P, T697G, W719R, V756Y, N848D, T883R,

T887K, F906A, A937E

F20P, I302D, S313D, A346D, E408D, D476R, Q489P, Y579W,

S636N, T697G, W719R, V756Y, A824D, N848D, V881Q, T887K,

F906A, A937E, T999R

F20P, I302D, S313D, E408D, D476R, Q489P, Y579W, I602T,

S636N, T697G, W719R, V756Y, A824D, N848D, V881Q, T887K,

N905D, F906A, A937E, T999R, A1037E, F1048W

F20P, K51Q, I302D, S313D, E408D, D476R, Q489P, Y579W,

I602T, S636K, A651P, T697G, W719R, V756Y, A824D, N848D,

T883R, T887K, F906A, S928D, A937E, A1037E

N216D, S313D, A346D, E408D, D476R, Q489P, A559P, Y579W,

I602T, F638N, A651P, A688G, T697G, W719R, V756H, R880K,

T887K, K921R, S928D, Y934G

F20P, I302D, S313D, A346D, E408D, D476R, Q489P, Y579W,

I602T, T697G, W719R, V756Y, N848D, V881Q, T887K, F906A,

A937E

N216D, S313D, E408D, D476R, Q489P, A559P, Y579W, I602T,

F638N, A651P, A688G, T697G, W719R, V756H, Q834E, R880K,

T887K, T892P, K921R, S928D, Y934G

F20P, I302D, S313D, E408D, D476R, Q489P, A559N, Y579W,

I602T, S636K, A651P, T697G, W719R, V756Y, N848D, T883R,

T887K, F906A, S928D, A937E

F20P, I302D, S313D, E408D, D476R, Q489P, Y579W, I602T,

S636K, A651P, T697G, W719R, V756Y, N848D, T883R, T887K,

F906A, A937E

F20P, I302D, S313D, E408D, Q416S, D476R, Q489P, A559N,

Y579W, I602T, S636K, A651P, T697G, W719R, V756Y, N848D,

T883R, T887K, F906A, A937E

F20P, I302D, S313D, E408D, D476R, Y579W, I602T, S636N,

T697G, W719R, V756Y, A824D, N848D, V881Q, T887K, F906A,

S928D, A937E, T999R, F1048W

10. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein said endoglucanase variant has activity on xanthan gum pre-treated with xanthan lyase.

11. The detergent composition comprising an endoglucanase variant according to claim 1 , wherein said variant has a half-life improvement factor (HIF) of >1.0 relative to the wild-type endoglucanase.

12. A method of washing an article comprising:

applying the detergent composition of claim 1 to an article; wherein the article is a laundry article, a surface, or combinations thereof; and

degrading xanthan gum from the article.