METHOD FOR TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS USING PULSED ELECTROMAGNETIC FIELD THERAPY
A method for controlling levels of glucose and lipids in the blood of a patient having non-alcoholic steatohepatitis (NASH) includes generating an electromagnetic signal and coupling the electromagnetic signal to a target structure in the patient's liver to a induce a pulsed magnetic field in the target structure. The signal may include bursts of sinusoidal, rectangular, chaotic, and/or random waveforms, having a frequency content in a range of about 0.01 Hz to about 100 MHz at about 1 to about 100,000 waveforms per second, a burst duration from about 1 μsec to about 100 msec, a burst repetition rate from about 0.01 to about 1000 bursts/second. The induced magnetic field may have a peak amplitude of between 2 and 20 μT. The treatment may be repeated between 1 and 3 times per day every day for at least one week.
1 . A method for controlling levels of glucose and lipids in the blood of a patient having non-alcoholic steatohepatitis, the method comprising:
generating a pulsed electromagnetic field;
applying the pulsed electromagnetic field in proximity to a target structure in the patient's liver for a predetermined treatment interval.
2 . The method of claim 1 , wherein the predetermined treatment interval is between 1 and 30 minutes.
3 . The method of claim 1 , wherein the predetermined treatment interval is between 10 and 20 minutes.
4 . The method of claim 1 , wherein the predetermined treatment interval is about 15 minutes.
5 . The method of claim 1 , wherein the treatment interval is repeated 1 to 12 times per day every day for a predetermined number of weeks.
6 . The method of claim 1 , wherein the treatment interval is repeated 3 times per day for a one to two week period.
7 . The method of claim 6 , wherein:
a one week treatment period results in the patient having higher levels of triglycerides, HDL cholesterol, and LDL cholesterol in the blood than a similar patient receiving a sham treatment over the same period.
8 . The method of claim 6 , wherein:
a two week treatment period results in the patient having a heigher level of glucose in the blood than a similar patient receiving a sham treatment over the same period.
9 . The method of claim 1 , wherein generating a pulsed electromagnetic field comprises emitting a signal comprising bursts of at least one of sinusoidal, rectangular, chaotic, and random waveforms, having a frequency content in a range of about 0.01 Hz to about 100 MHz at about 1 to about 100,000 waveforms per second, having a burst duration from about 1 μsec to about 100 msec, and having a burst repetition rate from about 0.01 to about 1000 bursts/second.
10 . The method of claim 9 , wherein the signal comprises bursts of a 27.12 MHz sinusoidal wave.
11 . The method of claim 9 , wherein the burst duration is at least .5 msec.
13 . The method of claim 9 , wherein the burst duration is about 2 msec.
12 . The method of claim 9 , wherein the burst repetition rate is between 1 and 20 bursts/sec.
13 . The method of claim 9 , wherein the burst repetition rate is between 1 and 10 bursts/sec.
14 . The method of claim 9 , wherein the burst repetition rate is about 2 burst/sec.
15 . The method of claim 9 , wherein the signal induces a magnetic field having a strength of between 2 and 20 μT in the target structure.
16 . The method of claim 9 , wherein the signal induces a magnetic field of about 5 μT in the target structure.
17 . The method of claim 6 , wherein each treatment interval is followed by an inter-treatment interval that is at least 6 times longer than the treatment interval.
18 . The method of claim 6 wherein each treatment interval is followed by an inter-treatment interval at least 12 times longer than the treatment interval.
19 . A method for controlling levels of glucose and lipids in the blood of a patient having non-alcoholic steatohepatitis, the method comprising:
emitting a pulsed electromagnetic a signal, wherein the signal comprises bursts of at least one of sinusoidal, rectangular, chaotic, and random waveforms, having a frequency content in a range of about 0.01 Hz to about 100 MHz at about 1 to about 100,000 waveforms per second, having a burst duration from about 1 μsec to about 100 msec, and having a burst repetition rate from about 0.01 to about 1000 bursts/second;
applying the pulsed electromagnetic field in proximity to a target structure in the patient's liver for a treatment interval of between 1 and 30 minutes; and
repeating the treatment interval between 1 and 12 times per day every day for a predetermined number of weeks, wherein each treatment interval is followed by an inter-treatment interval that is at least 6 times longer than the treatment interval
20 . The method of claim 19 , wherein:
the signal comprises bursts of a a 27.12 MHz sinusoidal wave, each burst having a duration of about 2 msec and a burst duration rate of about 2 bursts/sec;
the signal induces a magnetic field of about 5 μT in the target structure;
the treatment interval is about 15 minutes, repeated 3 times a day for one to two weeks; and
the inter-treatment interval is about three hours.