IP Library › Granted Patent US 11,433,160
Granted Patent B2
US 11,433,160 · App. 16/659,830 · Granted Sep 6, 2022

Formed sheet product and hemostatic material

Inventors: Yukako Kageyama (Hino, JP); Kentaro Fujinaga (Hino, JP); Ayuko Yamaguchi (Hino, JP); Yusuke Akiyama (Hino, JP); Akitoshi Oono (Hino, JP); Susumu Honda (Hino, JP); Makoto Satake (Hino, JP); Hiroaki Kaneko (Hino, JP); Takayuki Imamura (Kikuchi, JP); Ryoichi Kawamura (Kikuchi, JP); Masaki Hirashima (Kikuchi, JP)
Assignees: TEIJIN LIMITED; KM BIOLOGICS CO., LTD.
A61L26/0066A61K38/363A61K38/4833A61L24/0015A61L24/0036A61L24/0042A61L24/043A61L26/009A61L26/0052A61L26/0085A61L2300/25A61L2300/252A61L2300/418A61L2400/04
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,433,160
App. No.
16/659,830
Granted
Sep 6, 2022
Kind
B2
Abstract

A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin and at least one polymer selected from the group consisting of an aliphatic polyester and a water-soluble polymer, and a laminated formed sheet product comprising a first polymer composition layer composed of fibrinogen and a water-soluble polymer and a second polymer composition layer composed of thrombin and an aliphatic polyester are provided. These formed products are applied onto a wound site and function as a hemostatic material.

Claims (6)

1. A formed sheet product of a polymer composition comprising at least one protein selected from the group consisting of fibrinogen and thrombin, and an aliphatic polyester, wherein at least one part of said at least one protein is incorporated into and is not covalently bonded to said aliphatic polyester, and

wherein the formed sheet product is manufactured from a suspension composed of a solution of the aliphatic polyester and particles of the protein.

2. The formed sheet product according to claim 1 , wherein the aliphatic polyester is selected from the group consisting of polyglycolic acid, polylactic acid, polycaprolactone, a copolymer thereof, and a mixture thereof.

3. The formed sheet product according to claim 1 , wherein the formed sheet product is a formed film product or a formed fiber product.

4. A hemostatic material comprising the formed sheet product according to claim 1 .

5. A tissue adhesive material or tissue closure material comprising the formed sheet product according to claim 1 .

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 4, 2024
From: TEIJIN LIMITED
To: KM BIOLOGICS CO., LTD.
Reel/Frame 068480/0793 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE ASSIGNEE'S ADDRESS PREVIOUSLY RECORDED AT REEL: 059539 FRAME: 0848. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jul 7, 2022
From: TEIJIN PHARMA LIMITED
To: TEIJIN LIMITED
Reel/Frame 060613/0067 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 8, 2022
From: TEIJIN PHARMA LIMITED
To: TEIJIN LIMITED
Reel/Frame 059539/0848 →
Priority Claims (5)
JP 2012-110391 · May 14, 2012 · national
JP 2012-110392 · May 14, 2012 · national
JP 2012-110393 · May 14, 2012 · national
JP 2012-110394 · May 14, 2012 · national
JP 2013-003273 · Jan 11, 2013 · national
Continuity (2)
Continuation 14399117
Related Publication 20200046877A1 · Feb 13, 2020